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Marcellina was the daughter of the prefect of Gaul and sister of St. Ambrose. She was born at Trier, Gaul. She went to Rome with her family when she was quite young, and was consecrated to a religious life by Pope Liberius in 353. She lived a life of great austerity, which St. Ambrose tried to persuade her to mitigate when she went to Milan to visit him. It was to Marcellina that he dedicated his treatise on virginity, Libri III de virginibus ad Marcellinam. Her feast day is July 17.
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