New super pill could prolong human longevity
By Catholic Online (NEWS CONSORTIUM)
3/3/2014 (3 years ago)
Catholic Online (www.catholic.org)
A new medical discovery in the form of a pill could ward off ageing has come closer to reality. A protein, called sirtuin 1, or SIRT1 has been found to extend the lives of mice and delayed the onset of age-related diseases. This could in turn lead to drugs that can apply to human subjects.
Both Sirtuin 1 and 2 proteins are involved in DNA repair and gene regulation, and may help to prevent diabetes, heart disease and cancer.
LOS ANGELES, CA (Catholic Online) - Researchers believe their experiments could lead to drugs that help to keep people younger and healthier. SIRT1, along with its sister protein, SIRT2 are known to play an important roles in metabolism across a wide range of species.
Both proteins are involved in DNA repair and gene regulation, and may help to prevent diabetes, heart disease and cancer.
Rafael de Cabo researchers, from the U.S. National Institutes of Health Researchers tested the effects of a SIRT1-activating molecule called SRT1720 on the health and lifespan of mice.
The test subjects that were fed a standard diet supplemented with 100 milligrams per kilogram of body weight of SRT1720 from the age of six months.
The researchers found that SRT1720 significantly extended the average lifespan of mice by 8.8 percent. Mice fed the molecule were found to weigh less and appeared slimmer, with better muscle function and co-ordination throughout their lives.
Further studies showed that SRT1720 supplementation led to a heart-protective lowering of harmful cholesterol and improved insulin sensitivity, which could help prevent diabetes. Another health benefit found were anti-inflammatory effects, which were also seen in various tissues. This is important because chronic low-level inflammation is believed to contribute to ageing and age-related diseases.
"Here, we show for the first time that a synthetic SIRT1 activator extends lifespan and improves health span of mice fed a standard diet," Dr de Cabo says.
"It illustrates that we can develop molecules that ameliorate the burden of metabolic and chronic diseases associated with ageing."
You may want to skip your next barbecue with this next bit of news: Previous research has found that eating barbecued, grilled or fried meat could increase the risk of being struck down by dementia.
Experts in the United States found that compounds called advanced glycation end products, or Ages, suppress the anti-ageing enzyme known as Sirt1.
Protein-rich foods that are cooked at very high temperatures raise the level of these harmful Ages in blood.
Copyright 2018 - Distributed by THE CALIFORNIA NETWORK
Pope Francis Prayer Intentions for JANUARY 2018
Religious Minorities in Asia. That Christians, and other religious minorities in Asian countries, may be able to practise their faith in full freedom.
Social media censorship is on the rise, prompting fears that Christian speech could be stifled. Recently, a Twitter engineer was caught on ... continue reading
A couple weeks ago, Luis Elizondo, the former Pentagon head of a virtual X-Files program within the Department of Defense, broke the ... continue reading
Last week, a story surged in the media that may serve as the best evidence yet that Earth is being visited by extraterrestrials. While most ... continue reading
A mysterious object passing through our solar system will be studied today to determine if it is transmitting a message. A team of ... continue reading
The self-driving trucks are coming soon. After years of predicting their imminent arrival on a highway near you, we finally have a date, ... continue reading
by Catholic Online
- St. Fabian: Saint of the Day for Saturday, January 20, 2018
- Science is transforming the pro-life debate for the better HD Video
- Daily Readings for Saturday, January 20, 2018
- Cardinal Dolan asks the faithful to pray against 'powers of darkness' ...
- 5 Things You Need To Know About 'Offering A Mass' For A Loved One
- Daily Reading for Monday, January 22nd, 2018 HD Video
- Most Americans want abortion restricted, if not outlawed
- Daily Reading for Tuesday, January 23rd, 2018 HD
- Daily Reading for Sunday, January 21st, 2018 HD
- Jobless claims are down - what does that mean for workers? HD
- Daily Reading for Saturday, January 20th, 2018 HD
Learn about Catholic world
Inform - Inspire - Ignite
Catholic Online Saints
Your saints explained
Catholic Online Prayers
Prayers for every need
Catholic Online Bible
Complete bible online
Catholic Online News
Your news Catholic eye
Today's bible reading
Products and services we offer
Catholic Online Shopping
Catholic medals, gifts & books
The California Network
Inspiring streaming service
Learn the Catholic way
Teacher lesson plans & resources
Support Free Education
Tax deductible support Free education