Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

9/2/2014 (2 weeks ago)

Catholic Online (www.catholic.org)

Blobs may hold key to fighting some diseases

Scientists in the U.S. are calling on the scientific community to up their efforts to determine the purpose and function of mysterious blobs in cells that have eluded understanding since they were first discovered 50 years ago.

Scientists are stepping up attempts at understanding the purpose of 'blobs' of protein within human cells.

Scientists are stepping up attempts at understanding the purpose of "blobs" of protein within human cells.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

9/2/2014 (2 weeks ago)

Published in Technology

Keywords: Cell, Science, Health, Technology


LOS ANGELES, CA (Catholic Online) - This request from the international community comes as some suspect that these blobs could play a key role in fighting diseases such as cancer.

You can be a light in the darkness with "prayer and action."


These blobs are known as assemblages, and consist of cloudy structures that consist of shifting collections of proteins.

"I want to know what these assemblages are doing in Ewing sarcoma, the disease I concentrate on-and I would think all other researchers who study human biology would want to know their functions in both health and disease," said Jeffrey Toretsky, a professor from Georgetown University.

With Professor Peter Wright, from The Scripps Research Institute in La Jolla, California, Toretsky compiled an overview of what is known about these assemblages and published it in the Journal of Cell biology.

"The 'blobs' are often-but not always-made up of intrinsically disordered proteins," they wrote.

This is counter to the behavior of most proteins, whom assume a specific shape that fits certain other molecules.

While the purpose of these blob proteins is not clear, they are not inactive. Rather, they seek each other out and form gel-like structures. These resulting assemblages can trap and interact with other proteins and even RNA-a system that transfers information between DNA and proteins.

"It is only in the last five years that researchers have begun recognizing that proteins without fixed structures may have important transitional properties that change based upon their local abundance in cells," Toretsky explained.

If these blobs do in fact play a role in disease, it might be possible to target them with a small-molecule drug, Toretsky believes.

"Current drug-discovery dogma suggests that it is very hard to make a small molecule to prevent two structured proteins from interacting," he said. "However, small molecules have a greater likelihood of disrupting intrinsically disordered protein-protein interactions.

"This review links together very basic biologic phenomena of protein interaction with the potential for new drug discovery. It's an exciting challenge."

---


Pope Francis: end world hunger through 'Prayer and Action'


© 2014 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for September 2014
Mentally disabled:
That the mentally disabled may receive the love and help they need for a dignified life.
Service to the poor: That Christians, inspired by the Word of God, may serve the poor and suffering.



Comments


More Technology

Apple takes a stand: They say they won't unlock iPhones, iPads for police Watch

Image of With their new policy -- not even Apple will be able to unlock the secrets held on their iPhones and iPads that the user does not wish to share --

By Catholic Online (NEWS CONSORTIUM)

Electronic industry leader Apple has taken a remarkable stand that will make them somewhat unpopular with law enforcement. The company declared this week that they will make it impossible for data from iPhones or iPads handed over to the police. This ... continue reading


This goofy looking jet is the key to Europe's airplane market Watch

Image of Airbus currently operates five Beluga airbuses, which are the primary way in which the company transports airplane parts.

By Catholic Online (NEWS CONSORTIUM)

The Airbus A300-600ST, more popularly known as the "Beluga" due to its resemblance to the Arctic whale, is celebrating the 20th anniversary of its first flight this month. LOS ANGELES, CA (Catholic Online) - The Beluga performs critical transportation roles in ... continue reading


New fossils may prove that mammals existed alongside dinosaurs Watch

Image of New fossils of early, squirrel-like mammals, found in China, have shown that mammals may have existed early then previously thought.

By Catholic Online (NEWS CONSORTIUM)

Fossils of three early mammalian species from over 200 million years ago suggests that dinosaurs and mammals did coexist on the Earth earlier than previously thought. LOS ANGELES, CA (Catholic Online) - The fossils of the squirrel-like creatures were discovered in ... continue reading


Make way for the 'Phablet:' Apple hopes to recapture trendsetters with world's first 'smartwatch' Watch

Image of Apple CEO Tim Cook talked about the Apple Watch during a special event at the Flint Center for the Performing Arts this week.

By Catholic Online - (NEWS CONSORTIUM)

The way of the future...is "phablets," which combines both features of smartphones and tablets. Apple, hoping to usurp the high tech throne from Asian rival Samsung will announce their first ever "smartwatch" along with two large-screen versions of the iPhone ... continue reading


British researchers may have just found the cure for multiple sclerosis! Watch

Image of A new study by researchers from Bristol University may have found a way to stop autoimmune diseases like multiple sclerosis or Type 1 diabetes.

By Catholic Online (NEWS CONSORTIUM)

A new study published in the journal Nature Communications shows that scientists may have discovered a way to stop autoimmune diseases like multiple sclerosis or Type 1 diabetes by retraining the immune system. LOS ANGELES, CA (Catholic Online) - The study was ... continue reading


Futuristic, super-fast sports car runs on saltwater Watch

Image of A four-seater, the car's 22-inch wheels sit just beneath impressive double gull-wing doors, in the manner of the classic DeLorean, that feature

By Catholic Online (NEWS CONSORTIUM)

Imagine, if you will - in the words of the late, great Rod Serling of "Twilight Zone" fame - a futuristic sports car that can go from zero to 60 miles per hour in less than three seconds - that runs entirely on saltwater. While sports cars are not known for ... continue reading


Scientists put out international plea to help figure out purpose of cellular protein 'blobs' Watch

Image of Scientists are stepping up attempts at understanding the purpose of

By Catholic Online (NEWS CONSORTIUM)

Scientists in the U.S. are calling on the scientific community to up their efforts to determine the purpose and function of mysterious blobs in cells that have eluded understanding since they were first discovered 50 years ago. LOS ANGELES, CA (Catholic Online) - ... continue reading


MARK OF THE BEAST: Microchip implants in humans becoming more viable Watch

Image of Chips are already being used to manage farm animals. Farmers can track sheep, pigs and horses as they move through a gate, weigh them instantly and make sure they are eating properly.

By Catholic Online (NEWS CONSORTIUM)

A microchip implanted on human beings has chilling implications, conjuring up images of the "Mark of the Beast" as mentioned in the Book of revelations. Such an accessory would certainly be a boon for a totalitarian society - but there are scientists who say ... continue reading


Google, Internet search engine - branches off with DRONE DELIVERY Watch

Image of Google engineers coupled with experts on unmanned aerial vehicles, called UAVs, safely carried out more than 30 test flights this month.

By Catholic Online (NEWS CONSORTIUM)

The unquestioned leader of Internet search engines, Google, has branched off into a most unexpected venture. Google is now considering delivery with drone aircraft, running its first test flights earlier this month as part of "Project Wing," a secretive, ... continue reading


What are these mysterious objects found underneath Stonehenge? Watch

Image of Using underground radar and 3D imaging technology, a new study has revealed that there are numerous monuments underneath the famous Stonehenge.

By Catholic Online (NEWS CONSORTIUM)

England's iconic and mysterious Stonehenge has just revealed a new mystery, as a first-of-its-kind study suggests that 15 previously undiscovered or poorly understood monuments lie hidden under the ancient monument and the surrounding countryside. LOS ANGELES, CA ... continue reading


All Technology News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Proverbs 3:27-34
27 Refuse no kindness to those who have a right to ... Read More

Psalm, Psalms 15:2-3, 3-4, 5
2 Whoever lives blamelessly, who acts uprightly, who ... Read More

Gospel, Luke 8:16-18
16 'No one lights a lamp to cover it with a bowl or ... Read More

Saint of the Day

Saint of the Day for September 22nd, 2014 Image

St. Thomas of Villanueva
September 22: Augustinian bishop. Born at Fuentellana, Castile, Spain, he was ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter