Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

1/29/2014 (7 months ago)

Catholic Online (www.catholic.org)

Epsilon toxin may be the culprit behind debilitating disease

According to a new study, multiple sclerosis, or as it more commonly known, MS may be triggered by a toxin produced by common bacteria found in food. An inflammatory disease of the central nervous system, MS is believed to be triggered in a genetically susceptible individual by a combination of one or more environmental factors. The triggers are not yet known.

Epsilon toxin is produced by certain strains of Clostridium perfringens, which is a spore-forming bacterium that is one of the most common causes of food borne illness.

Epsilon toxin is produced by certain strains of Clostridium perfringens, which is a spore-forming bacterium that is one of the most common causes of food borne illness.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

1/29/2014 (7 months ago)

Published in Health

Keywords: Multiple sclerosis, foodborne illnesses, epsilon toxin


LOS ANGELES, CA (Catholic Online) - U.S. scientists using previous studies now suggested that epsilon toxin, which is produced by common bacteria, could in fact trigger MS.

Known as an autoimmune condition, something goes wrong with the patient's immune system. This can cause multiple sections of the brain and spinal column to become damaged and hardened.

Please pray for the sick.

MS is also characterized by blood brain permeability and demyelination, a process in which the insulating myelin sheaths of neurons are damaged.

"We provide evidence that supports epsilon toxin's ability to cause permeability and show that epsilon toxin kills the brain's myelin producing cells, oligodendrocytes - the same cells that die in MS lesions," microbiologist Jennifer Linden of Weill Cornell Medical College, says. Linden presented the new research at the ASM Biodefense and Emerging Diseases Research Meeting.

"We also show that epsilon toxin targets other cells types associated with MS inflammation such as the retinal vascular and meningeal cells . Epsilon toxin may be responsible for triggering MS."

Epsilon toxin is produced by certain strains of Clostridium perfringens, which is a spore-forming bacterium that is one of the most common causes of food borne illness.

Previous studies have also suggested that C. perfringens, in particular, epsilon toxin, may play a role in triggering MS.

Dr. Linden and her colleagues discovered C. perfringens type B, a strain that is not known to infect humans and produces the epsilon toxin in a 21-year-old woman who was experiencing a flare-up of her MS.

Studying the behavior of the toxin in mice focusing on which cells it targeted, Linden and her colleagues discovered that the toxin did target the brain cells associated with MS pathology, but that was not all they found.

"Originally, we only thought that epsilon toxin would target the brain endothelium cells and oligodendrocytes; we just happened to notice that it also bound to and killed meningeal cells (of neurons).

"This was exciting because it provides a possible explanation for meningeal inflammation and subpial cortical lesions exclusively observed in MS patients, but not fully understood.'

Testing local foods for the presence of C. perfringens and the toxin gene, off the 37 food samples, 13.5 percent were positive for bacteria and almost three per cent were positive for the epsilon toxin gene.

The development of a neutralizing antibody or vaccine directed against the epsilon toxin might stop the progression of the disease or prevent it from even developing, Linden added.

Pope Francis calls for your 'prayer and action'...

---


Pope Francis: end world hunger through 'Prayer and Action'


2014 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for August 2014
Refugees:
That refugees, forced by violence to abandon their homes, may find a generous welcome and the protection of their rights.
Oceania: That Christians in Oceania may joyfully announce the faith to all the people of that region.



Comments


More Health

Do you eat pomegranates? Well here's a few reasons why you should Watch

Image of Pomegranates contain the chemical punicalagin, a form of a chemical compound known as polyphenol, which may help to prevent the inflammation that destroys brain cells known as micrologia.

By Catholic Online (NEWS CONSORTIUM)

An ingredient in pomegranate may help stop the spread of Alzheimer's disease, scientists from the University of Huddersfield claim. LOS ANGELES, CA (Catholic Online) - The chemical punicalagin, a form of a chemical compound known as polyphenol, helps prevent the ... continue reading


NEW HOPE IN EBOLA CRISIS: U.S. doctor released from hospital - cured Watch

Image of

By Catholic Online (NEWS CONSORTIUM)

Contracting the deadly African virus while he worked to save their lives, Dr. Kent Brantly became one of the handful of people from the United States to contract Ebola. Receiving treatment back in the U.S., Brantly walked out of the hospital to the waiting arms ... continue reading


HEALTH DISASTER: Is nearly half of all Americans destined to contract diabetes? Watch

Image of The irony of the situation is that Americans are generally living longer, which is a factor in their increased lifetime chance of developing type 2 diabetes. Americans are also not dying in the same proportions that they were, because of better treatment.

By Catholic Online (NEWS CONSORTIUM)

Has the United States reached the tipping point with diabetes and obesity? A shocking new study claims that nearly HALF of all Americans, if trends continue, will develop type 2 diabetes in the near future. Public Health England, in their most recent report ... continue reading


First large-scale shipment of new malaria drug shipped out Watch

Image of The recent shipment marks a new phase in the fight against the mosquito-borne disease.

By Catholic Online (NEWS CONSORTIUM)

Just as virulent - as far more easily transmitted than Ebola, malaria is making new inroads to populations in sub-Saharan Africa. In response, French drug maker Sanofi has announced the delivery of large-scale batches of an antimalarial drug made using ... continue reading


Very accurate colon cancer in-home detection kit approved by FDA Watch

Image of  The U.S. Food and Drug Administration has approved a new at-home, DNA-based stool test that screens for colorectal cancer with more than 90 percent accuracy.

By Catholic Online (NEWS CONSORTIUM)

Screening for colon cancer is frequently arduous and invasive. Patients need to fast prior to a colonoscopy, and the colonoscopy itself be highly uncomfortable and not always accurate. There's now good news for those at risk. The U.S. Food and Drug ... continue reading


You'll think twice before you put this dangerous chemical back in your mouth! Watch

Image of Colgate's Total brand of toothpaste contains the chemical triclosan, which has been proven to cause disruptions in the endocrine system in mice and rats.

By Catholic Online (NEWS CONSORTIUM)

A top-selling toothpaste uses the chemical triclosan which has been linked to cancer-cell growth and disrupted development in animals, and regulators are still reviewing whether or not it's safe to pt in soap, cutting boars and toys, while many consumer companies ... continue reading


New diabetes drug could help us all: Found effective in preventing cancer Watch

Image of Scientists who studied more than 180,000 people found a

By Catholic Online (NEWS CONSORTIUM)

According to a new study, a drug widely prescribed to treat type 2 diabetes could help us all live longer. Said drug, metformin, which controls glucose levels, may also stave off cardiovascular disease and cancer, regardless if the person is diabetic. LOS ... continue reading


Mutated gene increases women's chance for breast cancer by threefold Watch

Image of Doctors also could recommend more aggressive surveillance for breast cancer, such as annual mammograms or MRI breast screening.

By Catholic Online (NEWS CONSORTIUM)

A new study has found that mutated versions of a gene called PALB2 can dramatically increase a woman's risk of breast cancer. Researchers say that women carrying the PALB2 mutation have a one in three chance of developing breast cancer by the age of 70. LOS ... continue reading


WAS WORLD'S THROAT CUT? Ebola vaccine research was earlier abandoned Watch

Image of It must also be noted that while the National Institutes of Health and the U.S. government often fund the early animal safety and efficacy testing of a vaccine, pharmaceutical companies typically fund the human clinical trials to take a drug or vaccine to market.

By Catholic Online (NEWS CONSORTIUM)

With increasing fears of the Ebola virus in West Africa and elsewhere, world governments are now frantically trying to contain the disease. What is not widely known is the fact that there had been work on finding a vaccine for Ebola four years ago, that was ... continue reading


PLAGUE STRIKES HOME: At least six people tested for Ebola in U.S. Watch

Image of Said individual, who has recently traveled to West Africa where the current outbreak is taking place is said to be under

By Catholic Online (NEWS CONSORTIUM)

At least six people within the continental United States have been tested for the dreaded Ebola virus, the deadly hemorrhagic disease tearing through West Africa. While all six people tested negative, the states in which these people were from remains a tightly ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, First Corinthians 2:1-5
1 Now when I came to you, brothers, I did not come ... Read More

Psalm, Psalms 119:97, 98, 99, 100, 101, 102
97 How I love your Law! I ponder it all day ... Read More

Gospel, Luke 4:16-30
16 He came to Nazara, where he had been brought up, ... Read More

Saint of the Day

Saint of the Day for September 1st, 2014 Image

St. Giles, Abbot
September 1: St. Giles, Abbot (Patron of Physically Disabled) Feast day - ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter