Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

7/11/2014 (2 years ago)

Catholic Online (www.catholic.org)

Stem cells used in study of retinitis pigmentosa to identify faulty genes

Retinitis pigmentosa, or RP is an inherited, degenerative eye disease that causes severe vision impairment and frequently leads to blindness. Affecting around one in 3,000 to 4,000 people, scientists have moved closer to a breakthrough in "personalized" treatments for a leading cause of blindness.

The age at which symptoms start is variable and the rate of deterioration often varies. In around half of all cases there are other family members with the condition.

The age at which symptoms start is variable and the rate of deterioration often varies. In around half of all cases there are other family members with the condition.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

7/11/2014 (2 years ago)

Published in Health

Keywords: Retinitis pigmentosa, night blindness, research


LOS ANGELES, CA (Catholic Online) - Individual gene therapies are being used to determine the factors which triggers inherited vision loss.

Researchers used "induced" stem cells, which were taken from ordinary skin cells to investigate patient-specific causes of RP. 

Join the fight to end world hunger, by going here --

By testing retinal cells created from the stem cells in the laboratory, scientists linked RP in two patients to mutations in a gene called MFRP. They then then used a virus to deliver normal copies of the gene into the retinal cells and restore their function.

The gene therapy was used in further experiments to rescue the vision of genetically modified mice with RP caused by the same problem.

"The use of patient-specific cell lines for testing the efficacy of gene therapy to precisely correct a patient's genetic deficiency provides yet another tool for advancing the field of personalized medicine," lead scientist Professor Stephen Tsang, from Columbia University in New York, says.

Symptoms of retinitis pigmentosa become apparent from early childhood, while others may not know they have it until later in life. Caused by abnormalities of the eye's photoreceptors or the pigmented cell later or the retina, the condition leads to gradual sight loss.

Those with the disease can experience night blindness while others will lose central vision causing the person to look sidelong at objects. RP is one of the most common forms of inherited loss in vision.

The age at which symptoms start is variable and the rate of deterioration often varies. In around half of all cases there are other family members with the condition.

The condition has been a difficult for researchers as 60 different genes have been linked to RP, making it a difficult disease to study.

Symptoms typically begin with night blindness after which peripheral vision is lost.

---


Pope Francis: end world hunger through 'Prayer and Action'


Copyright 2016 - Distributed by THE CALIFORNIA NETWORK

Pope Francis Prayer Intentions for SEPTEMBER 2016
Universal:
Centrality of the Human Person: That each may contribute to the common good and to the building of a society that places the human person at the center.
Evangelization: Mission to Evangelize: That by participating in the Sacraments and meditating on Scripture, Christians may become more aware of their mission to evangelize.



Comments


More Health

Birth control leads to depression, increased risk of breast cancer and more Watch

Image of What impact does birth control have on your hormones?

By (CNA/EWTN News)

For the millions of women using hormonal birth control, side effects are nothing new. Washington D.C. (CNA/EWTN News) - Headaches, mood swings and weight gain are all commonly reported side effects, not to mention more serious problems such as blood clots and ... continue reading


God is good! Man learns to walk after FOUR DECADES in wheelchair Watch

Image of Rufino Borrego (not pictured) no longer requires his wheelchair.

By Kenya Sinclair (CALIFORNIA NETWORK)

Rufino Borrego was only 13-years-old when he was diagnosed with muscular dystrophy, leading to 43-years of his life spent confined to a wheelchair. LOS ANGELES, CA (Catholic Online) - Borrego was diagnosed by doctors at a Lisbon hospital and he spent the majority of ... continue reading


5 things you NEED to know about drug-resistant superbugs and antimicrobial resistance Watch

Image of Do YOU know how to protect yourself?

By Kenya Sinclair (CALIFORNIA NETWORK)

The United Nations General Assembly voted to take "a broad coordinated approach" to antimicrobial resistance, which is growing at such an alarming rate, millions are expected to die by 2050. LOS ANGELES, CA (Catholic Online) - "This is only the fourth time a health ... continue reading


St. Padre Pio helps dying newborn miraculously recover after 25 DAYS on life support Watch

Image of (Photo by: Ciara Wilkinson/Irish Mirror)

By Abigail James (CALIFORNIA NETWORK)

Three-month-old Caitlin Dooley suffered from a life-threatening heart condition since the day she was born. Just when the Dooley family began to lose hope, St. Padre Pio stepped in. LOS ANGELES, CA (Catholic Online) - According to the Irish Mirror, at just 11-days-old, ... continue reading


Pray for the children with brain cancer - the number 1 cancer responsible for childhood deaths Watch

Image of The number one cancer killing children in the US is of the brain.

By Kenya Sinclair (CALIFORNIA NETWORK)

A new federal report revealed brain cancer is now the leading cancer killer of children in the United States. LOS ANGELES, CA (Catholic Online) - Sally Curtin and her colleagues at the NCHS, part of the CDC, discovered brain tumors and leukemia are the two  most ... continue reading


Harvard scientists reveal surprising footage dubbed 'Hollywood wizardry' Watch

Image of Harvard scientists release a timelapse video featuring the evolution of antibiotic resistance.

By Kenya Sinclair (CALIFORNIA NETWORK)

Harvard scientists have finally released video evidence of the astounding strength of nature. LOS ANGELES, CA (Catholic Online) - Scientists have long attempted to find a cure for bacteria-related illness such as the common cold but in a new video recently released by ... continue reading


'The killing of an innocent human being is always wrong'- Doctors suggest killing coma patients to harvest organs Watch

Image of Is it right to kill coma patients for their organs?

By Kevin J. Jones (CNA/EWTN News)

There are severe ethical shortcomings in a British doctor's proposal to help unconscious patients die so their organs can be used for transplants, one critic has said. London, England (CNA/EWTN News) - "The killing of an innocent human being is always wrong - even when ... continue reading


Don't blame the free market for drug prices out of control -- blame corruption Watch

Image of Prescription drug prices are higher in the USA than anywhere in the world.

By Marshall Connolly (CALIFORNIA NETWORK)

It's no secret that prescription drug prices in the U.S. are out of control. Americans pay far more for their drugs than people in any other industrialized nation. This excess needs correction before it collapses the American healthcare system. LOS ANGELES, CA ... continue reading


'Loneliness has to be everybody's business' - How being alone can affect your mental and physical health Watch

Image of You don't have to be alone.

By Kenya Sinclair (CALIFORNIA NETWORK)

In this age of connection, researchers have discovered a surprising rise in people suffering debilitating loneliness - but there is hope. LOS ANGELES, CA (Catholic Online) - Fortune describes chronic loneliness as a "modern-day epidemic."John Cacioppo, the director of ... continue reading


Scientists resurrect an ancient killer plague, but why? Watch

Image of The Plague of Justinian killed almost 15 percent of the world's population in the sixth century AD.

By Marshall Connolly (CALIFORNIA NETWORK)

Scientists have reconstructed the genome of an ancient bacteria that was responsible for one of the most devastating plagues in human history. The Plague of Justinian has been resurrected, at least in the lab. LOS ANGELES, CA (California Network) - The Plague of ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

Daily Readings

Reading 1, Job 38:1, 12-21; 40:3-5
1 Then from the heart of the tempest Yahweh gave Job his answer. He ... Read More

Psalm, Psalms 139:1-3, 7-8, 9-10, 13-14
1 [For the choirmaster Of David Psalm] Yahweh, you examine me and know ... Read More

Gospel, Luke 10:13-16
13 'Alas for you, Chorazin! Alas for you, Bethsaida! For if the miracles ... Read More

Saint of the Day

Saint of the Day for September 30th, 2016 Image

St. Jerome
September 30: St. Jerome, who was born Eusebius Hieronymous ... Read More