Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

11/6/2013 (1 year ago)

Catholic Online (www.catholic.org)

'Cryopreservation' is risky process, reserved for smaller groups of tissues

The transplantation of human organs always carries a high amount of risk. Available organs from donors must be quickly identified, and technicians must race the organs to patients at hospitals many miles away. Time is of the essence. The ability to freeze human organs would be a godsend, but is currently not feasible. Now - researchers are bringing this process closer to fruition.

The transplantation of human organs always carries a high amount of risk. Available organs from donors must be quickly identified, and technicians must race the organs to patients at hospitals many miles away.

The transplantation of human organs always carries a high amount of risk. Available organs from donors must be quickly identified, and technicians must race the organs to patients at hospitals many miles away.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

11/6/2013 (1 year ago)

Published in Health

Keywords: Cryptopreservation, human organs, cells, ice crystals


LOS ANGELES, CA (Catholic Online) - Researchers from Villanova University have now discovered how ice crystals invade and damage biological material during the freezing process. Once this obstacle is surmounted, freezing complex human tissues such as donor organs could be a very real option for physicians.

Called "cryopreservation," the procedure involves cooling human tissues to sub-zero temperatures. While this frozen state effectively blocks chemical reactions from happening and lets them remain viable for medical use later on.

"If you can cryopreserve tissue or even organs, then you have a way of storing them and of transporting them," senior author Dr. Jens Karlsson, of the department of mechanical engineering at Villanova University says.

"Now if you want to do a (lung) transplantation, you're rushing the harvest organ from one hospital to another by helicopter, and you only have a few hours to do it. But if you're able to preserve the tissue, then you have as much time as you want and you can really find the best match for the tissue and transport it over much longer distances."

Cryopreservation is currently a risky process, only reserved for the conservation of smaller groups of tissues or individual cells, such as embryos and stem cells.

Freezing larger biological tissues is far more cumbersome, as these materials often contain large amounts of water, which form ice crystals when frozen. This causes significant damage to the cells and tissue.

In order to find out how ice interacts with cells as they freeze, Karlsson and his team utilized a video cryomicroscrope. The process allowed them to observe the freezing process using high-speed imaging.

"We could record what happens and play it back in slow motion and really see in great detail what the interactions are between the ice, and cells in the tissue," Karlsson said.

The team then monitored the freezing events of genetically modified cells, some of which contained certain junction proteins and some of which did not. These junction proteins either suppressed or encouraged the formation of the cells' gap junctions and tight junctions- channels that connect adjacent cells together.

Gap junctions. On the other hand directly connected the cytoplasm of two cells, while tight junctions provide an even closer connection by firmly stitching together the cells' plasma membranes.

The researchers found that when the gap junctions were suppressed in the cells, the ice still spread freely throughout the tissue. Extremely snug tight junctions played a significant role in allowing the ice to infiltrate the cells.

A birth foretold: click here to learn more!

---


Pope Francis: end world hunger through 'Prayer and Action'


Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for February 2015
General Intention:
That prisoners, especially the young, may be able to rebuild lives of dignity.
Missionary Intention: That married people who are separated may find welcome and support in the Christian community.



Comments


More Health

Paging Dr. Frankenstein! Human head transplant possible in just two years Watch

Image of Dr. Sergio Canavero said he would expect the patient to be able to move and feel their face when they awoke, they would speak with the same voice. They would be able to walk within a year.

By Catholic Online (NEWS CONSORTIUM)

The procedure would be beneficial to humankind - and help those who are stricken with devastating disease. When we learn of the process, however, the first thing to pop into our heads is hunchbacked assistants and green-faced monsters. A human heads transplant ... continue reading


Shocking 'medical miracle' birth startles doctors and parents Watch

Image of (Cedars-Sinai Medical Center in Los Angeles)

By Abigail James (NEWS CONSORTIUM)

Now dubbed a "medical miracle," the birth of Silas Philips took doctors by surprise when he was born still inside his amniotic sac. Silas' birth miracle is extremely rare, only 1 in 80,000 births are similar to his. LOS ANGELES, CA (Catholic Online) - When his mother ... continue reading


New pill dramatically cuts risk for AIDS transmission in homosexual men Watch

Image of Some 545 HIV-negative gay men, who were sexually active and had recently had unprotected sex, were recruited to the study.

By Catholic Online (NEWS CONSORTIUM)

A daily pill, pre-exposure prophylaxis, or PrEP has been found to dramatically cut a person's risk of contracting HIV. Following a trial in the United Kingdom, advocates say the drug must be made available as soon as possible. LOS ANGELES, CA (Catholic Online) ... continue reading


AT RISK: Formula-fed babies at risk for ingesting ARSENIC Watch

Image of While arsenic in home tap water was a source of the naturally occurring chemical, poisonous in large doses, the formula itself was a contributing factor as well.

By Catholic Online (NEWS CONSORTIUM)

Breastfeeding has long been deemed the healthiest nursing option for newborns. A new study from Dartmouth College bears this out: According to researchers, arsenic levels were more than seven times higher in formula-fed babies than in breastfed ones. LOS ... continue reading


Unbelievable: Secret to success may lie in your sleeping habits Watch

Image of New studies show the most successful people receive little sleep at night.

By Abigail James (NEWS CONSORTIUM)

Traditional research advises people between 18-64 years old get seven to nine hours of sleep for a healthy lifestyle. New studies are showing that some of the most successful and smartest people in the world rarely even get half of that amount of sleep a night. LOS ... continue reading


Closing door and throwing away the key: HIV vaccine proves SUCCESSFUL in monkeys Watch

Image of Given the drug, the test monkeys were able to fend off high, repeated doses of the simian version of the disease.

By Catholic Online (NEWS CONSORTIUM)

Comparing it to locking up an intruder and throwing away the key, scientists now say they have created an anti-HIV drug so powerful that it could work as a vaccine. The test trials have proven to be highly successful in Macaque monkeys.  LOS ANGELES, CA ... continue reading


Women are at risk: Dementia affects more women than men, quickly becoming number one killer Watch

Image of

By Abigail James (NEWS CONSORTIUM)

500,000 women are affected by dementia. This is compared to the 350,000 men who are afflicted. Dementia is quickly surpassing breast cancer or heart disease; it is becoming the newest disease that favors women. LOS ANGELES, CA (Catholic Online) - Not only is dementia ... continue reading


Unable to feel pain, rare medical condition haunts man's life with horrifying injuries Watch

Image of Undergoing a series of tests throughout his lifetime, it was not until 2011 that Steve Pete was given the genetic tests confirmed he and his brother Chris had genetic mutations of the SCN9A gene.

By Catholic Online (NEWS CONSORTIUM)

Steve Pete's parents knew something was wrong with their child when he chewed part of his tongue off while he was a baby. Pete suffers from a rare condition known as congenital analgesia, where he is unable to feel pain. Unable to detect physical discomfort, ... continue reading


Don't throw away those glasses yet! Lasik eye surgery found imperfect, even dangerous Watch

Image of The results of bad eye laser surgery include the necessitating of several glasses for both near and far-sighted vision, dry eyes and blurring of light sources at night.

By Catholic Online (NEWS CONSORTIUM)

Lasik eye surgery, where vision defects are cured with lasers, has a high success rate. However, anyone who undergoes the procedure must carefully weigh the risks. Those for whom the procedure fails must wear several glasses afterwards and suffer ailments. The ... continue reading


SAVING THOUSANDS OF LIVES: Medicare to cover lung cancer screening Watch

Image of A report projected that paying for lung cancer screening would cost Medicare $9 billion over five years, or about $3 per month per beneficiary.

By Catholic Online (NEWS CONSORTIUM)

A move that many are hailing as one that will save tens of thousands of lives, Medicare said this week that it will pay for lung cancer screening for people at the highest risk. Lung cancer remains the top cancer death for men in the United States and ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Psalms 116:10, 15, 16-17, 18-19
4 I pleaded with Yahweh my God and made this ... Read More

Psalm, Psalms 116:10, 15, 16-17, 18-19
15 Costly in Yahweh's sight is the death of his ... Read More

Gospel, Mark 9:2-10
2 Six days later, Jesus took with him Peter and James ... Read More

Reading 2, Romans 8:31-34
31 After saying this, what can we add? If God is for ... Read More

Saint of the Day

Saint of the Day for March 1st, 2015 Image

St. David
March 1: According to tradition, St. David was the son of King Sant of ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter