Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

5/16/2011 (4 years ago)

Catholic Online (www.catholic.org)

Gene called KLF14 linked to type 2 diabetes and cholesterol levels

A gene linked to diabetes and cholesterol has been declared by scientists as a "master switch" that controls other genes found in fat in the body. Researchers say that by studying and targeting the gene, identified as KLF14 should help in the search for treatments for obesity-related diseases.

Obesity-related diseases already account for nearly 10 percent of medical spending in the United States, an estimated $147 billion a year. Type 2 diabetes, usually linked to poor diet and lack of exercise, is also reaching epidemic levels worldwide as rates of obesity rise.

Obesity-related diseases already account for nearly 10 percent of medical spending in the United States, an estimated $147 billion a year. Type 2 diabetes, usually linked to poor diet and lack of exercise, is also reaching epidemic levels worldwide as rates of obesity rise.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

5/16/2011 (4 years ago)

Published in Health

Keywords: KLF14, obesity, diabetes, glucose, gene research


LOS ANGELES, CA (Catholic Online) - As reported in the journal Nature Genetics, the British researchers say that since fat plays an important role in peoples' susceptibility to metabolic diseases like obesity, heart disease and diabetes, the regulating gene could be target for drugs to treat such illnesses. "This is the first major study that shows how small changes in one master regulator gene can cause a cascade of other metabolic effects in other genes," Tim Spector of King's College London, who led the study, says. Obesity has become the worldwide scourge of the 21st century. More than half a billion people -- one in 10 adults worldwide, are obese. The numbers have doubled since the 1980s, as even the poorer nations - where starvation remains a real concern; have become effected by the obesity epidemic. Obesity-related diseases already account for nearly 10 percent of medical spending in the United States, an estimated $147 billion a year. Type 2 diabetes, usually linked to poor diet and lack of exercise, is also reaching epidemic levels worldwide as rates of obesity rise. Researchers analyzed more than 20,000 genes in fat samples taken from under the skin of 800 British female twin volunteers and found a link between the KLF14 gene and the levels of many other distant genes found in fat tissue, showing that KLF14 acts as a master switch to control these genes. The findings were confirmed with 600 fat samples from a separate group of people from Iceland. In a report of their study, the researchers explained that other genes found to be controlled by KLF14 are linked to a range of metabolic traits, including body mass index, obesity, cholesterol, insulin and glucose levels. "KLF14 seems to act as a master switch controlling processes that connect changes in the behavior of subcutaneous fat to disturbances in muscle and liver that contribute to diabetes and other conditions," Mark McCarthy from Britain's Oxford University says. "We are working hard...to understand these processes and how we can use this information to improve treatment of these conditions."

---


Pope Francis: end world hunger through 'Prayer and Action'


Copyright 2015 - Distributed by THE CALIFORNIA NETWORK

Pope Francis Prayer Intentions for April 2016
Universal:
Small Farmers: That small farmers may receive a just reward for their precious labor.
Evangelization: African Christians: That Christians in Africa may give witness to love and faith in Jesus Christ amid political-religious conflicts.



Comments


More Health

Are you bored? Here's why and here's how to fix it! Watch

Image of Boredom is usually caused by overstimulation.

By Marshall Connolly (CALIFORNIA NETWORK)

Are you bored? Is boredom a constant visitor in your life? If so, you could be suffering from overstimulation. Fortunately, the condition is curable. Here's how. LOS ANGELES, CA (California Network) - Most Americans are chronically bored. According to British ... continue reading


2 billion in danger of Zika this summer - are YOU prepared? Watch

Image of Zika is expected to spread across the tropic and subtropical areas in Asia, Africa and the Americas (123rf).

By Kenya Sinclair (CALIFORNIA NETWORK)

Scientists at the University of Oxford and the Institute for Health Metrics and Evaluation in Seattle estimate 2.2 billion people are at risk of contracting Zika. LOS ANGELES, CA (Catholic Online) - A map published in the journal eLife indicated sections of South ... continue reading


Health insurance premiums about to rise for those who pay them Watch

Image of Obamacare is becoming more painful than ever.

By David Drudge (CALIFORNIA NETWORK)

Insurance companies are telling Obama and the American people they must permit them to raise rates substantially, or they will pull out of the Obamacare markets. This is more proof Obamacare is designed to fail. LOS ANGELES, CA (California Network) - Insurance ... continue reading


Sweaty billboards save lives? Watch

Image of The new billboard prototypes have been erected in Zika-infested countries (Posterscope/NBS).

By Kenya Sinclair (CALIFORNIA NETWORK)

Hate mosquitoes? Love living the bug-free life? These crazy sweaty billboards are exactly what you need! LOS ANGELES, CA (Catholic Online) - Billboards have been created to smell like human sweat while simultaneously shooting out carbon dioxide to attract, trap and ... continue reading


Is pornography the new cigarettes? Watch

Image of

By Marshall Connolly (CALIFORNIA NETWORK)

Is pornography the new cigarettes? According to some research, the answer is yes, prompting Utah officials to declare pornography a public health crisis. LOS ANGELES, CA (California Network) - In the 1950s, nearly half of all Americans smoked cigarettes. There was ... continue reading


Can't sleep? Then don't read this horrifying article about KILLER insomnia Watch

Image of Fatal Familial Insomnia is a horrifying killer. About 40 families in the world have the deadly genetic mutation in their genes.

By Marshall Connolly (CALIFORNIA NETWORK)

Imagine one night, you prepare for bed, but you cannot sleep. It's the latest in a spat of insomnia that seems to be worsening. The sleepless nights turn into days, then weeks without sleep. Eventually, you lose the ability to sleep altogether. What's happening and ... continue reading


First Zika infection between gay couple reported in the United States Watch

Image of Zika affects everyone - regardless of age, gender or sexual orientation (Queerty).

By Kenya Sinclair (CALIFORNIA NETWORK)

The Centers for Disease Control (CDC) confirmed the case of sexually transmitted Zika virus between two men in Dallas, Texas. LOS ANGELES, CA (Catholic Online) - One of the men had traveled to Venezuela, where he was bitten by a Zika=infected mosquito.When he returned ... continue reading


Health insurance premiums to increase dramatically in 2017 as Obamacare inches towards failure Watch

Image of Obamacare is bound to fail. Only 1 person is surprised.

By Marshall Connolly (CALIFORNIA NETWORK)

Health insurers are asking permission to raise their rates next year as they warn about the financial stability of Obamacare. Some are threatening to drop out of the Obamacare marketplace because they cannot make money. LOS ANGELES, CA (California Network) - Although ... continue reading


'It's everywhere around us': Deadly bacteria makes its way across the midwest Watch

Image of Cases of Elizabethkingia have been spreading across the Midwest (freestockphotos).

By Kenya Sinclair (CALIFORNIA NETWORK)

A common and usually harmless bacteria has resulted in at least 20 deaths in the Midwest. Meanwhile, 57 people have been diagnosed with the bacterial infection, which originated in Illinois and has since traveled to Wisconsin and Michigan. LOS ANGELES, CA (Catholic ... continue reading


Your prescription co-pays are about to skyrocket. Here's why Watch

Image of We're addicted and the manufacturers are greedy. This is why your prices will continue to skyrocket.

By Marshall Connolly (CALIFORNIA NETWORK)

Spending on prescription drugs is expected to pick up over the next four years according to a report from the health information company, IMH Health Holdings. Americans may spend as much as $640 billion for their medications in 2020. LOS ANGELES, CA (California ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

the FEED
by Catholic Online

Daily Readings

Reading 1, Acts 15:22-31
22 Then the apostles and elders, with the whole church, decided to choose ... Read More

Psalm, Psalms 57:8-9, 10-12
8 Awake, my glory, awake, lyre and harp, that I may awake the ... Read More

Gospel, John 15:12-17
12 This is my commandment: love one another, as I have loved ... Read More

Saint of the Day

Saint of the Day for April 29th, 2016 Image

St. Catherine of Siena
April 29: St. Catherine of Siena was born during the ... Read More