Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

10/4/2013 (1 year ago)

Catholic Online (www.catholic.org)

Called ALN-PCS, cuts levels of 'bad' cholesterol by more than half

A fresh, new treatment called ALN-PCS is able to cut levels of "bad" cholesterol by more than half. Which is typically reduced by statins. The new drug is being heralded as a breakthrough to patients who are unable to take statins.

People were randomly assigned to receive either an injection of ALN-PCS or saline as a placebo. It was found that a single dose of the drug cut LDL levels by up to 57 percent.

People were randomly assigned to receive either an injection of ALN-PCS or saline as a placebo. It was found that a single dose of the drug cut LDL levels by up to 57 percent.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

10/4/2013 (1 year ago)

Published in Health

Keywords: Statins, ALN-PCS, cholesterol, study


LOS ANGELES, CA (Catholic Online) - The trial tests in human beings have proven the potential benefits. The new drug blocks the production of a protein that destroys receptors that normally clear harmful LDL cholesterol from the blood.

Human tests involved 32 healthy volunteers with high LDL, or "bad" cholesterol. People were randomly assigned to receive either an injection of ALN-PCS or saline as a placebo. It was found that a single dose of the drug cut LDL levels by up to 57 percent.

AS was published in the medical journal The Lancet, the bigger the dose of the drug, the greater the reduction in LDL.

ALN-PCS, likely be developed in a pill form, "could be used for the one in five heart disease patients intolerant or resistant to statins, or to enhance their effects," trial investigator Kevin Fitzgerald, from Alnylam Pharmaceuticals says.

ALN-PCS works by blocking the production of the cholesterol regulator PCSK9, which is a protein that destroys low-density lipoprotein, or LDL receptors that normally clear LDL cholesterol from the blood.

Studies have proven that the mutations resulting in a rise in PCSK9 activity lead to a major increase in LDL cholesterol which contributes to the build up of plaque inside blood vessels, while genetic variants that cause less PCSK9 activity lower cholesterol dramatically.
 
"People with extremely high cholesterol are at increased risk of a heart attack and this approach could offer new hope for those who are resistant to statins," Professor Peter Weissberg, medical director at the British Heart Foundation says.

"These initial results add to growing evidence that blocking the action of a certain protein can dramatically lower 'bad' LDL cholesterol. More research is now needed to confirm this approach is both safe and effective at preventing heart attacks in the long term before it becomes widely available."

Click here to learn about our Saint Michael the Archangel conference this Nov 1-3!

---


Pope Francis: end world hunger through 'Prayer and Action'


Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for May 2015
Universal:
That, rejecting the culture of indifference, we may care for our neighbours who suffer, especially the sick and the poor.
Evangelization: That Mary's intercession may help Christians in secularized cultures be ready to proclaim Jesus.


Rosaries, Crosses, Prayer Cards and more... by Catholic Shopping .com


Comments


More Health

Revolutionary! Robotic arm controlled by thought provides breakthrough for paralyzed Watch

Image of

By Catholic Online (NEWS CONSORTIUM)

An exciting new breakthrough in robotics may now enable the paralyzed to command helpmates with everyday activity. The breakthrough came in form of 34-year-old Erik Sorto, paralyzed from the neck down after being shot in the back 13 years ago. Thanks to a ... continue reading


Ancient Chinese plant 'thunder god vine' studied as miracle drug for obesity Watch

Image of In developed nations, where food is inexpensive and plentiful, obesity has been an ongoing problem. Obesity causes heart disease, diabetes and increases the risk for heart attack and stroke.

By Catholic Online (NEWS CONSORTIUM)

A traditional Chinese medicine known as "thunder god vine" is being heralded by some scientists as the new miracle drug in the war against obesity. Scientists in an article published in the medical journal Cell last week said an extract made from the plant ... continue reading


Brain reset: Scientists uncover unusual way to get rid of brain disorders Watch

Image of

By Atarah Haely (NEWS CONSORTIUM)

By implanting special cells that emit GABA into the brains of adult mice scientists found a way to cure certain brain disorders, like lazy eye. Initially an almost impossible endeavor, the experiment led a team of scientists to a way to reset the brain and basically ... continue reading


Health in the United States: Which cities are the healthiest? Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

The American College of Sports Medicine has recently released their 2015 American Fitness Index, naming the top three fittest and the least fit cities in the entire United States. MUNTINLUPA, PHILIPPINES (Catholic Online) -  Among the thousands of cities surveyed ... continue reading


Nebraska orders STATE OF EMERGENCY over H5N2 avian flu virus Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

A type of avian flu, and unfortunately the most lethal to hit the United States, has posed several concerns for farmers and scientists. So far, the H5N2 strain of the bird flu virus has already killed 15,000 turkeys in Minnesota alone. Now, over 33 million birds in 16 ... continue reading


Why a handshake just might save your life Watch

Image of Handshakes may be able to determine your risk for heart disease or other illnesses.

By Matt Waterson (NEWS CONSORTIUM)

Are you worried about a heart attack or stroke? Well there may be an easy way to tell if you are at greater risk for either of these diseases, are near death or seriously ill, and you don't need anything more than a hand and a partner. LOS ANGELES, CA (Catholic ... continue reading


Are you afraid of needles? Scientist believes he found way to reduce injection pain Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

A lot of people, the young and old alike, are really frightened of getting injections, even just the thought of it. The good news is that scientists have discovered a simple answer. MUNTINLUPA, PHILIPPINES (Catholic Online) - Spanish scientists believe that holding ... continue reading


Woman gives shocking birth to baby born with bladder outside of body Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

Born with a rare congenital defect, Baby Lila underwent a unique surgery, shortly after she was born with her bladder outside the body. This defect was detected when the doctor couldn't find her bladder in a sonogram conducted during the 22-week prenatal appointment. ... continue reading


What do healthy people eat for breakfast? 11 healthy breakfast choices from dietitians and experts Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

What we eat in the mornings have an effect on our energy levels throughout the day. Here, registered dietitians, personal trainers, health editors and nutritionists, suggest healthy breakfasts for a healthy morning start, with some help from BuzzFeed. MUNTINLUPA, ... continue reading


NOT-SO HAPPY PILLS: Half a million patients die every year from psychiatric drugs Watch

Image of Professor Peter Gotzsche, research director at Denmark's Nordic Cochrane Center says the use of most antidepressants and dementia drugs could be discontinued without harm.

By Catholic Online (NEWS CONSORTIUM)

A Danish scientist has come forward to proclaim that mood enhancers, "happy pills" and other psychiatric drugs are frequently deadly - killing half a million people a year. Furthermore, he says that these medications are usually ineffective - not producing the ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Sirach 35:1-12
1 One who keeps the Law multiplies offerings; one who ... Read More

Psalm, Psalms 50:5-6, 7-8, 14, 23
5 'Gather to me my faithful, who sealed my covenant ... Read More

Gospel, Mark 10:28-31
28 Peter took this up. 'Look,' he said to him, 'we ... Read More

Saint of the Day

Saint of the Day for May 26th, 2015 Image

St. Philip Neri
May 26: If one had to choose one saint who showed the humorous side of ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter