Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

6/24/2013 (2 years ago)

Catholic Online (www.catholic.org)

Almost always fatal virus found blocked by designer version of hormone

Ebola, the horrific African virus that causes the patient's internal organs to go into meltdown has long been a scourge on the continent. Named after the river in Africa, the virus is 90 percent fatal. Scientists, now working with a variant of the female hormone estrogen, have found a way to potentially block the advance of the virus.

Ebola has long been feared as a disease that could be used in biological warfare by terrorists.

Ebola has long been feared as a disease that could be used in biological warfare by terrorists.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

6/24/2013 (2 years ago)

Published in Health

Keywords: Ebola, estrogen, inhibitors, SERMS, biological warfare


LOS ANGELES, CA (Catholic online) - Scientists stumbled upon estrogen as a potential weapon against Ebola while looking to find new uses for old drugs.

Researchers at the U.S. Army Medical Research Institute of Infectious Diseases in Maryland and at the University of Virginia in Charlottesville screened 2,000 existing drugs, in search for chemical compounds that were effective against Ebola.

It was discovered that a number of human-made drugs, including selective estrogen receptor modulators, or SERMS, blocked Ebola's entry into cells in lab cultures and in mice.

Scientists note that it wasn't the estrogen drugs' hormonal activity that halted the Ebola virus, however.

Lisa Johansen, director of research programs at Zalicus, a biotechnology in Cambridge, Massachusetts says that it was the compound's chemical structure, and the structure of a number of other drugs, that hindered the microorganism. 

"I think that's one of the things that are exciting . When we looked at our inhibitors; we found that a lot of them are entry inhibitors. And a lot of them have the structure even though the mechanism is for something completely unrelated," Johansen said.

Designer drugs designed to act like estrogen without negative side effects, SERMS have acted as the frontline for defense against a host of infectious diseases. For example, Tamoxifen is an older SERM used to treat breast cancer and the newer Reloxifen is approved for the prevention and treatment of the bone-weakening condition osteoporosis.

Both have potentially serious side effects such as an increased risk of other types of cancer. Johansen envisions using SERMS and other repurposed compounds in a number of situations to prevent infection and death.

"I think they could be used both by a civilian population where outbreaks are as well as potentially by the military if they were in an area where there was an outbreak and they went in to intercede, or if somebody used them for bio-warfare," Johansen said.

Ebola has long been feared as a disease that could be used in biological warfare by terrorists. A search to prevent Ebola infection has been long ongoing. An article on using estrogen drugs and other compounds to prevent Ebola virus infection has been recently published in the latest issue of Science Translational Medicine.

---


Pope Francis: end world hunger through 'Prayer and Action'


Copyright 2016 - Distributed by THE CALIFORNIA NETWORK

Pope Francis Prayer Intentions for May 2016
Universal:
Respect for Women: That in every country of the world, women may be honored and respected and that their essential contribution to society may be highly esteemed.
Evangelization: Holy Rosary: That families, communities, and groups may pray the Holy Rosary for evangelization and peace.



Comments


More Health

Scientists play God in controversial move to revive the dead Watch

Image of Can scientists bring the dead back to life (Pinterest)?

By Kenya Sinclair (CALIFORNIA NETWORK)

It sounds like the plot to a science fiction story but scientists are about to attempt to bring twenty certified dead people back to life. LOS ANGELES, CA (Catholic Online) - Bioquark Inc., a biotech company, has received ethical permission to bring twenty brain-dead ... continue reading


Vatican teams up with United States to fight cancer Watch

Image of Pope Francis and Joe Biden talk cancer research at Vatican.

By Kenya Sinclair (CALIFORNIA NETWORK)

U.S. Vice President Joe Biden paid Pope Francis a little visit on Friday to talk cancer and Christian persecution. LOS ANGELES, CA (Catholic Online) -  Biden traveled to the Vatican to attend a summit on regenerative medicine. While at the Vatican, Biden pushed ... continue reading


Fountain of youth discovered: Immortality no longer a myth Watch

Image of Doctor explains theory to keep humans alive for centuries (Pinterest).

By Kenya Sinclair (CALIFORNIA NETWORK)

If given the option, would YOU choose to live forever? LOS ANGELES, CA (Catholic Online) - Dr. Aubrey de Grey, the co-founder and chief science officer for Strategies for Engineered Negligible Senescense (SENS) Research Foundation, believes the ongoing research ... continue reading


Are you bored? Here's why and here's how to fix it! Watch

Image of Boredom is usually caused by overstimulation.

By Marshall Connolly (CALIFORNIA NETWORK)

Are you bored? Is boredom a constant visitor in your life? If so, you could be suffering from overstimulation. Fortunately, the condition is curable. Here's how. LOS ANGELES, CA (California Network) - Most Americans are chronically bored. According to British ... continue reading


2 billion in danger of Zika this summer - are YOU prepared? Watch

Image of Zika is expected to spread across the tropic and subtropical areas in Asia, Africa and the Americas (123rf).

By Kenya Sinclair (CALIFORNIA NETWORK)

Scientists at the University of Oxford and the Institute for Health Metrics and Evaluation in Seattle estimate 2.2 billion people are at risk of contracting Zika. LOS ANGELES, CA (Catholic Online) - A map published in the journal eLife indicated sections of South ... continue reading


Health insurance premiums about to rise for those who pay them Watch

Image of Obamacare is becoming more painful than ever.

By David Drudge (CALIFORNIA NETWORK)

Insurance companies are telling Obama and the American people they must permit them to raise rates substantially, or they will pull out of the Obamacare markets. This is more proof Obamacare is designed to fail. LOS ANGELES, CA (California Network) - Insurance ... continue reading


Sweaty billboards save lives? Watch

Image of The new billboard prototypes have been erected in Zika-infested countries (Posterscope/NBS).

By Kenya Sinclair (CALIFORNIA NETWORK)

Hate mosquitoes? Love living the bug-free life? These crazy sweaty billboards are exactly what you need! LOS ANGELES, CA (Catholic Online) - Billboards have been created to smell like human sweat while simultaneously shooting out carbon dioxide to attract, trap and ... continue reading


Is pornography the new cigarettes? Watch

Image of

By Marshall Connolly (CALIFORNIA NETWORK)

Is pornography the new cigarettes? According to some research, the answer is yes, prompting Utah officials to declare pornography a public health crisis. LOS ANGELES, CA (California Network) - In the 1950s, nearly half of all Americans smoked cigarettes. There was ... continue reading


Can't sleep? Then don't read this horrifying article about KILLER insomnia Watch

Image of Fatal Familial Insomnia is a horrifying killer. About 40 families in the world have the deadly genetic mutation in their genes.

By Marshall Connolly (CALIFORNIA NETWORK)

Imagine one night, you prepare for bed, but you cannot sleep. It's the latest in a spat of insomnia that seems to be worsening. The sleepless nights turn into days, then weeks without sleep. Eventually, you lose the ability to sleep altogether. What's happening and ... continue reading


First Zika infection between gay couple reported in the United States Watch

Image of Zika affects everyone - regardless of age, gender or sexual orientation (Queerty).

By Kenya Sinclair (CALIFORNIA NETWORK)

The Centers for Disease Control (CDC) confirmed the case of sexually transmitted Zika virus between two men in Dallas, Texas. LOS ANGELES, CA (Catholic Online) - One of the men had traveled to Venezuela, where he was bitten by a Zika=infected mosquito.When he returned ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

the FEED
by Catholic Online

  • Arising from Sleep HD Video
  • St. Thomas HD Video
  • 28 killed in refugee camp targeted by Assad's missiles
  • Daily Readings for Saturday, May 07, 2016
  • Pope Francis to EU: 'tear down the walls'
  • St. Rose Venerini: Saint of the Day for Saturday, May 07, 2016
  • 'The Evil': Exorcism classes forced on Spanish students

Daily Readings

Reading 1, Acts 18:9-18
9 One night the Lord spoke to Paul in a vision, 'Be fearless; speak out ... Read More

Psalm, Psalms 47:2-3, 4-5, 6-7
2 For Yahweh, the Most High, is glorious, the great king over all the ... Read More

Gospel, John 16:20-23
20 'In all truth I tell you, you will be weeping and wailing while the ... Read More

Saint of the Day

Saint of the Day for May 6th, 2016 Image

Bl. Edward Jones
May 6: Blessed Edward Jones and Anthony Middleton, ... Read More