Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

8/7/2014 (1 year ago)

Catholic Online (

Women with PALB2 mutation has one in three chance of developing breast cancer

A new study has found that mutated versions of a gene called PALB2 can dramatically increase a woman's risk of breast cancer. Researchers say that women carrying the PALB2 mutation have a one in three chance of developing breast cancer by the age of 70.

Doctors also could recommend more aggressive surveillance for breast cancer, such as annual mammograms or MRI breast screening.

Doctors also could recommend more aggressive surveillance for breast cancer, such as annual mammograms or MRI breast screening.


By Catholic Online (NEWS CONSORTIUM)

Catholic Online (

8/7/2014 (1 year ago)

Published in Health

Keywords: Breast cancer, PALB2, gene mutation, masectomy

LOS ANGELES, CA (Catholic Online) - British researchers in the latest issue of the New England Journal of Medicine say that the risk is even higher for women with a family history of breast cancer, the investigators found.

"If a mutation carrier has a strong family history, the risk would go up to about six in 10 by age 70," senior study author Marc Tischkowitz, a researcher with the department of medical genetics at the University of Cambridge, says.

SAVE Iraqi Christians from Genocide --

PALB2, with this new information, has been placed just behind the BRCA1 and BRCA2 genes as a top genetic risk factor for breast cancer, Tischkowitz adds.

Women who carry a mutated form of either of the BRCA genes have a 45 percent to 65 percent risk of breast cancer by age 70, according to the U.S. National Cancer Institute.

The PALB2 gene was first identified by researchers in 2006, and it was further associated with breast cancer in a study published in 2007, Tischkowitz said.

The new research proves the first solid evidence regarding the breast cancer risk associated with PALB2. According to Dr. Roger Greenberg, an associate professor of cancer biology with the Abramson Family Cancer Research Institute, this discovery empowers women who are susceptible to breast cancer.

"She can better make that decision based on the likelihood she could get cancer," Greenberg said. "I would frame it as a very relevant question for PALB2 carriers."

Armed with this knowledge, Greenberg says, women with a PALB2 mutation can talk with their doctor about whether they should undergo a mastectomy to reduce their breast cancer risk. Such surgery has been shown to reduce cancer risk by 90 percent.

Doctors also could recommend more aggressive surveillance for breast cancer, such as annual mammograms or MRI breast screening, Tischkowitz said.


Pope Francis: end world hunger through 'Prayer and Action'

Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for October 2015
That human trafficking, the modern form of slavery, may be eradicated.
Evangelization: That with a missionary spirit the Christian communities of Asia may announce the Gospel to those who are still awaiting it.


More Health

America drinks less soda: The soda industry sees an all-time-low in sales Watch

Image of The soda industry is changing.


Around five years ago, the soda industry fought back against Mayor Michael A. Nutter's proposal of imposing soda taxes in Philadelphia. Soda lobbyists back then organized protests and came up with campaign contributions to local politicians, with the assistance of ... continue reading

5 things people need to know about breast cancer Watch

Image of


Breast cancer is the most prevalent kind of disease that has been affecting women from all over the world. The World Health Organization estimated around 508,000 women die of this disease every year.  LOS ANGELES, CA (Catholic Online) - While some women fall prey ... continue reading

Early detection test can lead to breast cancer diagnoses before cancer appears Watch

Image of Breast Cancer Awareness Month.


A recent study may make it possible to detect breast cancer before the disease develops. Researchers clarified, however, that the study was based on genetic changes from samples taken from healthy breasts and cancerous breasts. LOS ANGELES, CA (Catholic Online) - The ... continue reading

ACLU sues Catholic hospital over refusal to abort children Watch

Image of The ACLU is insisting that Catholic hospitals abort still-living children.

By Catholic Online (NEWS CONSORTIUM)

The ACLU is suing Trinity Health Corporation, a Michigan-based Catholic hospital chain, because the organization refuses to perform abortions. The suit is similar to one brought by the ACLU in 2013, that case was dismissed by a Federal court. LOS ANGELES, CA (Catholic ... continue reading

Baby born with rare medical mystery thrives Watch

Image of Baby Angelito was born with two tubes for a nose.


Baby Angelito was born with two tubes in place of a nose but his doctors are optimistic about his condition.  LOS ANGELES, CA (Catholic Online) - Daily Mail reported the medical mystery as well as Angelito's doctors' belief the infant will soon appear normal.The ... continue reading

20-million-year old flea carrying bubonic plague may be real reason dinosaurs went extinct Watch

Image of The Black Death plague devastated entire populations (Interfoto/Alamy)


Preserved in amber, a 20-million-year-old flea is believed to contain an ancient form of one of the world's deadliest bacteria: Black Death.  LOS ANGELES, CALIFORNIA (Catholic Online) - According to the Journal of Medical Entomology, the fossilized bacteria is ... continue reading

Baby born missing majority of skull miraculously beats the odds, reaches first birthday Watch

Image of


Doctors said that Jaxon Buell only had a few days to live after his birth. The boy was born with a rare condition called the Microhydranencephaly, which left the majority of his skull unable to form. Despite the odds, Jaxon is strong and recently celebrated a milestone ... continue reading

New dangerous cluster of Legionnaires' disease reported in the Bronx Watch

Image of Legionnaires' disease is a lung bacteria that causes flue-like muscle pain, headaches, fevers, drowsiness, chills and in some cases delirium.

By Kenya Sinclair (NEWS CONSORTIUM)

A new cluster of Legionnaires' disease has been reported in the Bronx and is not related to the cluster outbreak in the Bronx earlier this summer that left 12 dead. NEW YORK CITY, NY (Catholic Online) - Fox5ny reported seven cases of Legionnaires' disease in the ... continue reading

Why fidgeting may actually be good for your health Watch

Image of


When you feel like fidgeting, don't worry about whether it's bad for you or not. New research shows that being restless and fidgeting at work can actually be good for your health. HOLLYWOOD, CA  (Catholic Online) - A series of studies showed that long periods of ... continue reading

What you need to know about the developmental process of Influenza Watch

Image of Inflammation associated with infection in the soft palate stimulates the sneezing and coughing. This propels the flu virus out of the mouth enabling it to spread easily.

By Catholic Online (NEWS CONSORTIUM)

Influenza, or "Flu," the respiratory ailment that hits hardest during the colder months, first develops on the roof of the mouth. That's the findings of researchers, who note that flu is then spread through coughs and sneezes. LOS ANGELES, CA (Catholic Online) ... continue reading

All Health News


Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

Daily Readings

Reading 1, Joel 4:12-21
12 'Let the nations rouse themselves and march to the ... Read More

Psalm, Psalms 97:1-2, 5-6, 11-12
1 Yahweh is king! Let earth rejoice, the many isles ... Read More

Gospel, Luke 11:27-28
27 It happened that as he was speaking, a woman in ... Read More

Saint of the Day

Saint of the Day for October 10th, 2015 Image

St. Francis Borgia
October 10: Francis was a young nobleman at the court of the King of Spain. ... Read More