Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

6/19/2014 (5 months ago)

Catholic Online (www.catholic.org)

Lower levels of triglyceride fats significantly reduces risk for heart disease

Mutations to a particular gene can dramatically lower the risk for heart attack, scientists have found. Researchers are now trying to develop drugs that target the gene in order to bring down the high rate of heart disease in the U.S. population.

Many people still have elevated triglycerides despite exercising, eating a low fat, low carbohydrate diet and taking statin drugs. An agent that targets APOC3 may further reduce blood fats, lowering the risk of heart attack.

Many people still have elevated triglycerides despite exercising, eating a low fat, low carbohydrate diet and taking statin drugs. An agent that targets APOC3 may further reduce blood fats, lowering the risk of heart attack.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

6/19/2014 (5 months ago)

Published in Health

Keywords: Mutations, gene, heart disease, good cholesterol, bad cholesterol


LOS ANGELES, CA (Catholic Online) - Recent studies have identified a gene called APOC3 in connection with the body's removal of triglycerides, a type of blood fat. Triglycerides, if they are not eliminated from the body, stick to blood vessels. They wind up stored in the hips and belly.

Elevated, triglycerides, or lipids, are thought to be a risk factor for heart disease. It's believed that approximately one in 150 people has mutations to the APOC3 gene that keep their triglyceride levels low.

Light up the darkness -- by going here --

A thorough investigation of 110,000 patient blood samples found those with the rare mutations had lower levels of triglyceride fats. These patients had a significantly reduced risk for the most common form of heart disease.

"We compared the heart attack rates of people who carried the mutations and those who didn't, and found that people who carried the mutations and had the lower triglycerides had 40 percent lower risk for heart attack," Sekar Kathiresan, director of Preventive Cardiology at Massachusetts General Hospital said. Kathiresan is an associate researcher at the Broad Institute of Biomedical Research and helped lead the study that identified four beneficial genetic mutations to the APOC3 protein. 

Elevated LDL, which is a blood fat commonly called "bad cholesterol" and its connection to heart disease is well-known. Experts know less about the benefits of raising HDL, or a blood lipid called "good cholesterol," as a hedge against heart attack, and the role triglycerides levels play in coronary artery disease.

The latest study of thousands of research subjects found elevated levels of good cholesterol were not protective, while low triglyceride levels appear to be.

With the discovery of the four mutations, researchers say they now have a target to develop a drug to lower blood lipids, which in turn will lead to the reduced risk of heart attack and stroke.

"Given that these people are naturally protected, if you develop a medicine that mimics this, then your chances of it working in terms of reducing the risk of heart attack are quite great," Kathiresan said.

Many people still have elevated triglycerides despite exercising, eating a low fat, low carbohydrate diet and taking statin drugs. An agent that targets APOC3 may further reduce blood fats, lowering the risk of heart attack, he said.

These findings were shared in two papers published this week in the New England Journal of Medicine.

---


Pope Francis: end world hunger through 'Prayer and Action'


2014 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for November 2014
Lonely people:
That all who suffer loneliness may experience the closeness of God and the support of others.
Mentors of seminarians and religious: That young seminarians and religious may have wise and well-formed mentors.



Comments


More Health

Brain weak spot that causes Alzheimer's begins in late adolescence Watch

Image of The study involved MRI brain scans on 484 healthy volunteers, aged between eight and 85 years, conducted by the Medical Research Council

By Catholic Online (NEWS CONSORTIUM)

According to scientists in the United Kingdom, the human brain has a weak spot for Alzheimer's disease and schizophrenia. Researchers pinpointed the region using scans. They say that the weak spot develops late in adolescence and degenerates early during aging. ... continue reading


Women beware! This fibroid removal process could just cost you your life! Watch

Image of Women who are seeking to have fibroids removed should have them tested for cancer first.

By Catholic Online (NEWS CONSORTIUM)

The U.S. Food and Drug Administration is warning women and physicians about a gynecologic device that has given women cancer. LOS ANGELES, CA (Catholic Online) - The FDA said that women who thought they had harmless fibroids found that their cancer was actually worse ... continue reading


GROSS! This was in his brain for four years! Watch

Image of A type of parasitic tapeworm, just a little over 0.3 inches in length, burrowed its way through the brain of a British man for four years.

By Catholic Online (NEWS CONSORTIUM)

In what has to be one of the most bizarre cases in recent medical history, a series of brain scans have been made which charts the path of a tiny parasitic tapeworm as it burrows its way through the brain of a British man. LOS ANGELES, CA (Catholic Online) - This ... continue reading


Obesity: It isn't just deadly, but each year it costs the globe TWO TRILLION! Watch

Image of Obesity is the third largest economic burden on the world, just $.1 trillion behind the costs of smoking and war and terrorism.

By Catholic Online (NEWS CONSORTIUM)

It should come as no surprise to anyone that terrorism and war hurt the global economy. What is incredible is that just behind them in terms of actual cost is smoking, and obesity. LOS ANGELES, CA (Catholic Online) - A new report from the economic consulting firm ... continue reading


Creation of John Paul II Medical Research Institute

By Alan B. Moy, MD

The Catholic Church has a long-standing history in health care, education and medical research. The Church was the first during the Middle Ages to create the university system and medical centers. Some of the early scientists were clergymen like Gregor Mendel, who was ... continue reading


Welcome to the horrifying future where women are used and abortion rampant Watch

Image of In the future, according to one dire prediction, babies will come from test tubes and sex will be purely for recreation.

By Catholic Online (NEWS CONSORTIUM)

The professor and chemist who invented the birth control pill has now claimed that advances in IVF will render the pill obsolete allowing people to plan pregnancies and engage in sex for recreational purposes only. LOS ANGELES, CA (Catholic Online) - Prof. Carl ... continue reading


Eat healthy, exercise and take statins - and live to be 120 years old Watch

Image of A

By Catholic Online (NEWS CONSORTIUM)

While immortality still remains out of reach by scientific standards, some scientists now say they have worked out how we could make it to 120. Exercising more, eating healthy and taking statins they claim are key to slowing the aging process. LOS ANGELES, CA ... continue reading


Dignity Health loses moral compass, settles overcharge scandal for $37 million Watch

Image of Catholic facilities, built and supported by Catholics, should remain Catholic.

By Catholic Online (NEWS CONSORTIUM)

The San Francisco-based Dignity Health hospital chain has agreed to pay a $37 million settlement to clear up allegations that they overcharged patients between 2006 and 2010. LOS ANGELES, CA (Catholic Online) - Dignity Health, a chain of 13 hospitals that was built by ... continue reading


'Elite controllers' claim that they can spontaneously 'cure' HIV Watch

Image of AIDS/HIV remains a scourge throughout the African continent and homosexual men in urban areas.

By Catholic Online (NEWS CONSORTIUM)

It's another claim made by researchers about a disease that continues to devastate the world. Scientists say they have uncovered the genetic mechanism which appeared to have led two HIV-infected men to experience a "spontaneous cure - and that the discovery ... continue reading


Sierra Leone sees Ebola cases 'spreading quickly' Watch

Image of There have been 2,413 Ebola deaths in Liberia, 1,510 in Sierra Leone, 1,018 in Guinea and eight in Nigeria.

By Catholic Online (NEWS CONSORTIUM)

While in other parts of West Africa, new Ebola cases appear to be tapering off, new cases continue to rise "frighteningly quickly" in areas of Sierra Leone. The international campaign group the Africa Governance Initiative, or AGI found that in rural parts of ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Revelation 20:1-4, 11--21:2
1 Then I saw an angel come down from heaven with the ... Read More

Psalm, Psalms 84:3, 4, 5-6, 8
3 Even the sparrow has found a home, the swallow a ... Read More

Gospel, Luke 21:29-33
29 And he told them a parable, 'Look at the fig tree ... Read More

Saint of the Day

Saint of the Day for November 28th, 2014 Image

St. Catherine Laboure
November 28: St. Catherine Laboure, virgin, was born on May 2, 1806. At an ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter