Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

5/9/2014 (1 year ago)

Catholic Online (www.catholic.org)

A key difference in the brains of male and female MS patients may explain gender disparity

Multiple sclerosis, or MS, is a degenerative disease that attacks the nervous system, overwhelmingly strikes females. Ninety percent of MS sufferers are female. Researchers now say that the key difference in the brains of male and female MS patients may explain why more women than men get the disease.

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision.

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

5/9/2014 (1 year ago)

Published in Health

Keywords: MS, amino, nervous system, gender disparity


LOS ANGELES, CA (Catholic Online) - Higher levels of protein S1PR2 were revealed in tests on the brains of female mice and dead women with MS than in male equivalents.

Research conducted at the Washington University School of Medicine found four times more women than men are currently diagnosed with MS. Health experts said they considered the findings as "really interesting."

Shop for mom today. Buy her a gift she'll love!

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision. There is no cure for MS, although there are treatments that can help in the early stages of the disease.

Examining patients with relapsing remitting MS, where people have distinct attacks of symptoms that then fade away either partially or completely, researchers in Missouri found that 85 percent of people with MS are diagnosed with this type.

Scientists studied the blood vessels and brains of healthy mice, mice with MS, and mice without the gene for S1PR2, a blood vessel receptor protein, to see how it affected MS severity. Researchers also looked at the brain tissue samples of 20 people after they had died. They found high levels of S1PR2 in the areas of the brain typically damaged by MS in both mice and people.

The study found that the activity of the gene coding for S1PR2 was positively correlated with the severity of the disease in mice.

Scientists said S1PR2 could work by helping to make the blood-brain barrier, in charge of stopping potentially harmful substances from entering the brain and spinal fluid and more permeable.

The study found that the more permeable barrier could lead attacking cells, which cause MS, into the central nervous system.

"We were very excited to find the molecule, as we wanted to find a target for treatment that didn't involve targeting the immune cells," Professor Robyn Klein, of the Washington University School of Medicine, said. "This link [between MS and S1PR2] is completely new - it has never been found before."

Klein said she did not know why the levels of S1PR2 were higher in women with MS, adding she had found estrogen had "no acute role." She said she's looking at taking her findings to clinical trials in the "next few years," she added.

Dr. Emma Gray, of the MS Society, said: "We don't yet fully understand why MS affects more women than men, and it's an area that's intrigued scientists, and people with MS, for many years.

"A number of theories have been suggested in the past, including the influence of hormones or possible genetic factors - and this study explores one such genetic factor in further detail, which is really interesting."

---


Pope Francis: end world hunger through 'Prayer and Action'


Copyright 2016 - Distributed by THE CALIFORNIA NETWORK

Pope Francis Prayer Intentions for May 2016
Universal:
Respect for Women: That in every country of the world, women may be honored and respected and that their essential contribution to society may be highly esteemed.
Evangelization: Holy Rosary: That families, communities, and groups may pray the Holy Rosary for evangelization and peace.



Comments


More Health

Vatican teams up with United States to fight cancer Watch

Image of Pope Francis and Joe Biden talk cancer research at Vatican.

By Kenya Sinclair (CALIFORNIA NETWORK)

U.S. Vice President Joe Biden paid Pope Francis a little visit on Friday to talk cancer and Christian persecution. LOS ANGELES, CA (Catholic Online) -  Biden traveled to the Vatican to attend a summit on regenerative medicine. While at the Vatican, Biden pushed ... continue reading


Fountain of youth discovered: Immortality no longer a myth Watch

Image of Doctor explains theory to keep humans alive for centuries (Pinterest).

By Kenya Sinclair (CALIFORNIA NETWORK)

If given the option, would YOU choose to live forever? LOS ANGELES, CA (Catholic Online) - Dr. Aubrey de Grey, the co-founder and chief science officer for Strategies for Engineered Negligible Senescense (SENS) Research Foundation, believes the ongoing research ... continue reading


Are you bored? Here's why and here's how to fix it! Watch

Image of Boredom is usually caused by overstimulation.

By Marshall Connolly (CALIFORNIA NETWORK)

Are you bored? Is boredom a constant visitor in your life? If so, you could be suffering from overstimulation. Fortunately, the condition is curable. Here's how. LOS ANGELES, CA (California Network) - Most Americans are chronically bored. According to British ... continue reading


2 billion in danger of Zika this summer - are YOU prepared? Watch

Image of Zika is expected to spread across the tropic and subtropical areas in Asia, Africa and the Americas (123rf).

By Kenya Sinclair (CALIFORNIA NETWORK)

Scientists at the University of Oxford and the Institute for Health Metrics and Evaluation in Seattle estimate 2.2 billion people are at risk of contracting Zika. LOS ANGELES, CA (Catholic Online) - A map published in the journal eLife indicated sections of South ... continue reading


Health insurance premiums about to rise for those who pay them Watch

Image of Obamacare is becoming more painful than ever.

By David Drudge (CALIFORNIA NETWORK)

Insurance companies are telling Obama and the American people they must permit them to raise rates substantially, or they will pull out of the Obamacare markets. This is more proof Obamacare is designed to fail. LOS ANGELES, CA (California Network) - Insurance ... continue reading


Sweaty billboards save lives? Watch

Image of The new billboard prototypes have been erected in Zika-infested countries (Posterscope/NBS).

By Kenya Sinclair (CALIFORNIA NETWORK)

Hate mosquitoes? Love living the bug-free life? These crazy sweaty billboards are exactly what you need! LOS ANGELES, CA (Catholic Online) - Billboards have been created to smell like human sweat while simultaneously shooting out carbon dioxide to attract, trap and ... continue reading


Is pornography the new cigarettes? Watch

Image of

By Marshall Connolly (CALIFORNIA NETWORK)

Is pornography the new cigarettes? According to some research, the answer is yes, prompting Utah officials to declare pornography a public health crisis. LOS ANGELES, CA (California Network) - In the 1950s, nearly half of all Americans smoked cigarettes. There was ... continue reading


Can't sleep? Then don't read this horrifying article about KILLER insomnia Watch

Image of Fatal Familial Insomnia is a horrifying killer. About 40 families in the world have the deadly genetic mutation in their genes.

By Marshall Connolly (CALIFORNIA NETWORK)

Imagine one night, you prepare for bed, but you cannot sleep. It's the latest in a spat of insomnia that seems to be worsening. The sleepless nights turn into days, then weeks without sleep. Eventually, you lose the ability to sleep altogether. What's happening and ... continue reading


First Zika infection between gay couple reported in the United States Watch

Image of Zika affects everyone - regardless of age, gender or sexual orientation (Queerty).

By Kenya Sinclair (CALIFORNIA NETWORK)

The Centers for Disease Control (CDC) confirmed the case of sexually transmitted Zika virus between two men in Dallas, Texas. LOS ANGELES, CA (Catholic Online) - One of the men had traveled to Venezuela, where he was bitten by a Zika=infected mosquito.When he returned ... continue reading


Health insurance premiums to increase dramatically in 2017 as Obamacare inches towards failure Watch

Image of Obamacare is bound to fail. Only 1 person is surprised.

By Marshall Connolly (CALIFORNIA NETWORK)

Health insurers are asking permission to raise their rates next year as they warn about the financial stability of Obamacare. Some are threatening to drop out of the Obamacare marketplace because they cannot make money. LOS ANGELES, CA (California Network) - Although ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

the FEED
by Catholic Online

  • St. James the Lesser: Saint of the Day for Tuesday, May 03, 2016
  • BREAKING: ISIS kills Navy SEAL
  • Prayer to Our Mother of Perpetual Help HD Video
  • Daily Readings for Tuesday, May 03, 2016
  • Pope Francis hit with sexually-explicit abuse on Twitter after ...
  • ICE gets more money, deports fewer illegals. Where's the money going?
  • Daily Reading for Wednesday, May 4th, 2016 HD Video

Daily Readings

Reading 1, First Corinthians 15:1-8
1 I want to make quite clear to you, brothers, what the message of the ... Read More

Psalm, Psalms 19:2-3, 4-5
2 day discourses of it to day, night to night hands on the ... Read More

Gospel, John 14:6-14
6 Jesus said: I am the Way; I am Truth and Life. No one can come to the ... Read More

Saint of the Day

Saint of the Day for May 3rd, 2016 Image

St. James the Lesser
May 3: St. James the Less, the author of the first ... Read More