Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

5/9/2014 (2 years ago)

Catholic Online (www.catholic.org)

A key difference in the brains of male and female MS patients may explain gender disparity

Multiple sclerosis, or MS, is a degenerative disease that attacks the nervous system, overwhelmingly strikes females. Ninety percent of MS sufferers are female. Researchers now say that the key difference in the brains of male and female MS patients may explain why more women than men get the disease.

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision.

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

5/9/2014 (2 years ago)

Published in Health

Keywords: MS, amino, nervous system, gender disparity


LOS ANGELES, CA (Catholic Online) - Higher levels of protein S1PR2 were revealed in tests on the brains of female mice and dead women with MS than in male equivalents.

Research conducted at the Washington University School of Medicine found four times more women than men are currently diagnosed with MS. Health experts said they considered the findings as "really interesting."

Shop for mom today. Buy her a gift she'll love!

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision. There is no cure for MS, although there are treatments that can help in the early stages of the disease.

Examining patients with relapsing remitting MS, where people have distinct attacks of symptoms that then fade away either partially or completely, researchers in Missouri found that 85 percent of people with MS are diagnosed with this type.

Scientists studied the blood vessels and brains of healthy mice, mice with MS, and mice without the gene for S1PR2, a blood vessel receptor protein, to see how it affected MS severity. Researchers also looked at the brain tissue samples of 20 people after they had died. They found high levels of S1PR2 in the areas of the brain typically damaged by MS in both mice and people.

The study found that the activity of the gene coding for S1PR2 was positively correlated with the severity of the disease in mice.

Scientists said S1PR2 could work by helping to make the blood-brain barrier, in charge of stopping potentially harmful substances from entering the brain and spinal fluid and more permeable.

The study found that the more permeable barrier could lead attacking cells, which cause MS, into the central nervous system.

"We were very excited to find the molecule, as we wanted to find a target for treatment that didn't involve targeting the immune cells," Professor Robyn Klein, of the Washington University School of Medicine, said. "This link [between MS and S1PR2] is completely new - it has never been found before."

Klein said she did not know why the levels of S1PR2 were higher in women with MS, adding she had found estrogen had "no acute role." She said she's looking at taking her findings to clinical trials in the "next few years," she added.

Dr. Emma Gray, of the MS Society, said: "We don't yet fully understand why MS affects more women than men, and it's an area that's intrigued scientists, and people with MS, for many years.

"A number of theories have been suggested in the past, including the influence of hormones or possible genetic factors - and this study explores one such genetic factor in further detail, which is really interesting."

---


Pope Francis: end world hunger through 'Prayer and Action'


Copyright 2016 - Distributed by THE CALIFORNIA NETWORK

Pope Francis Prayer Intentions for August 2016
Universal:
Sports: That sports may be an opportunity for friendly encounters between peoples and may contribute to peace in the world.
Evangelization: Living the Gospel: That Christians may live the Gospel, giving witness to faith, honesty, and love of neighbor.



Comments


More Health

Miraculous face transplant restores faceless firefighter's faith in life Watch

Image of Patrick Harden before his face transplant.

By Abigail James (CALIFORNIA NETWORK)

Fifteen years ago, volunteer firefighter Patrick Hardison suffered extreme facial burns while responding to a house fire. He lost a large portion of his face, including his eyelids, ears, lips, hair and most of his nose. LOS ANGELES, CA (Catholic Online) - Hardison, ... continue reading


'I lead a simple and disciplined life': Fit and healthy monk reveals secret to long life Watch

Image of The secret to a long life? One monk tells all (Dibyangshu Sarkar/AFP).

By Kenya Sinclair (CALIFORNIA NETWORK)

An Indian monk claiming to be 120-years-old has revealed his secret to a long, healthy life. LOS ANGELES, CA (Catholic Online) - Swami Sivananda appears to be a physically fit and his clean bill of health suggests he has led a long, healthy life.Sivananda plans to ... continue reading


ANOTHER insurer drops out of Obamacare as system continues to collapse Watch

Image of Aetna is the next insurer to drop out of Obamacare.

By David Drudge (CALIFORNIA NETWORK)

As Aetna pulls out of the Obamacare marketplace across most of the country, the moral failure of the Affordable Care Act becomes apparent. The ACA is neither affordable or sustainable. It is a complete failure that worsens with time. LOS ANGELES, CA (California ... continue reading


50 PERCENT INCREASE! Obamacare close to collapse, or success, depending on how you view it Watch

Image of Obamacare will only get worse, it can never get better because the government pays with a blank check each year.

By Marshall Connolly, (NEWS CONSORTIUM)

The cost of Obamacare continues to skyrocket, surpassing all expectations. Obamacare is inching closer to failure. LOS ANGELES, CA (California Network) - Obamacare is inching closure to failure, or success, depending on its aim. If Obamacare was designed to provide ... continue reading


'Myself and my family are indebted to him for life': How one priest's decision began a life-saving movement Watch

Image of Fr Davis Chiramel began a beautiful movement in India.

By Kenya Sinclair (CALIFORNIA NETWORK)

A Bishop, nun and thirteen clerics have decided to follow Father Davis Chiramel's lead when he gave the gift of life to a poor electrician. LOS ANGELES, CA (Catholic Online) - According to <a ... continue reading


'Dr. Frankenstein' to conduct world's first human head transplant Watch

Image of Valery Spiridonov is set to become the world's first human transplant patient (EPA).

By Kenya Sinclair (CALIFORNIA NETWORK)

Dr. Sergio Canavero, nicknamed Dr. Frankenstein, believes he can conduct a controversial operation to give a terminally ill man one more chance at life. LOS ANGELES, CA (Catholic Online) - Valery Spiridonov suffers from the very serious muscular atrophy disease ... continue reading


HIV outbreak spreads across US - Obama administration scrambles to control it Watch

Image of What has led to the spread of HIV (Avert)?

By Kenya Sinclair (CALIFORNIA NETWORK)

The United States enters a prescription opioid and heroin epidemic while the Obama Administration attempts to control it. LOS ANGELES, CA (Catholic Online) - The Guardian reported an alarming increase in an ongoing HIV outbreak across the United States.The primary ... continue reading


SEX BAN - British tourists advised to practice abstinance while visiting US Watch

Image of Zika can be spread through sexual contact or mosquito bites (Reuters).

By Kenya Sinclair (CALIFORNIA NETWORK)

Britain warns citizens against visiting the United States following a breakout of the Zika virus. LOS ANGELES, CA (Catholic Online) - According to the Telegraph, Public Health England (PHE) advised all British tourists visiting Florida should abstain from sexual ... continue reading


Doctor's orders - Do THIS to prevent a stroke Watch

Image of How can you prevent a stroke?

By Kenya Sinclair (CALIFORNIA NETWORK)

Did you know 90 percent of all strokes are preventable? What would you do to live a longer, healthier life? LOS ANGELES, CA (Catholic Online) - According to the Population Health Research Institute (PHRI), ten risk factors can be modified to prevent 9 of ten strokes ... continue reading


Sticker Shock! Here's how much Obamacare REALLY costs, per person! Watch

Image of Obamacare is bitter medicine for those who have to pay for it.

By David Drudge (CALIFORNIA NETWORK)

There's more proof the Affordable Care Act is anything but affordable. The national tab for healthcare, per person now exceeds $10,000. It may be because the goal of Obamacare is to fail and push the nation into a socialist, single-payer system. LOS ANGELES, CA ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

the FEED
by Catholic Online

Daily Readings

Reading 1, First Corinthians 1:17-25
17 After all, Christ sent me not to baptise, but to preach the gospel; ... Read More

Psalm, Psalms 33:1-2, 4-5, 10, 11
1 Shout for joy, you upright; praise comes well from the ... Read More

Gospel, Matthew 25:1-13
1 'Then the kingdom of Heaven will be like this: Ten wedding attendants ... Read More

Saint of the Day

Saint of the Day for August 26th, 2016 Image

St. Teresa of Jesus Jornet Ibars
August 26: Foundress of the Little Sisters of the Poor. Born ... Read More