Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

5/9/2014 (1 year ago)

Catholic Online (www.catholic.org)

A key difference in the brains of male and female MS patients may explain gender disparity

Multiple sclerosis, or MS, is a degenerative disease that attacks the nervous system, overwhelmingly strikes females. Ninety percent of MS sufferers are female. Researchers now say that the key difference in the brains of male and female MS patients may explain why more women than men get the disease.

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision.

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

5/9/2014 (1 year ago)

Published in Health

Keywords: MS, amino, nervous system, gender disparity


LOS ANGELES, CA (Catholic Online) - Higher levels of protein S1PR2 were revealed in tests on the brains of female mice and dead women with MS than in male equivalents.

Research conducted at the Washington University School of Medicine found four times more women than men are currently diagnosed with MS. Health experts said they considered the findings as "really interesting."

Shop for mom today. Buy her a gift she'll love!

MS typically attacks the nerves in the brain and spinal cord, which causes problems with muscle movement, balance and vision. There is no cure for MS, although there are treatments that can help in the early stages of the disease.

Examining patients with relapsing remitting MS, where people have distinct attacks of symptoms that then fade away either partially or completely, researchers in Missouri found that 85 percent of people with MS are diagnosed with this type.

Scientists studied the blood vessels and brains of healthy mice, mice with MS, and mice without the gene for S1PR2, a blood vessel receptor protein, to see how it affected MS severity. Researchers also looked at the brain tissue samples of 20 people after they had died. They found high levels of S1PR2 in the areas of the brain typically damaged by MS in both mice and people.

The study found that the activity of the gene coding for S1PR2 was positively correlated with the severity of the disease in mice.

Scientists said S1PR2 could work by helping to make the blood-brain barrier, in charge of stopping potentially harmful substances from entering the brain and spinal fluid and more permeable.

The study found that the more permeable barrier could lead attacking cells, which cause MS, into the central nervous system.

"We were very excited to find the molecule, as we wanted to find a target for treatment that didn't involve targeting the immune cells," Professor Robyn Klein, of the Washington University School of Medicine, said. "This link [between MS and S1PR2] is completely new - it has never been found before."

Klein said she did not know why the levels of S1PR2 were higher in women with MS, adding she had found estrogen had "no acute role." She said she's looking at taking her findings to clinical trials in the "next few years," she added.

Dr. Emma Gray, of the MS Society, said: "We don't yet fully understand why MS affects more women than men, and it's an area that's intrigued scientists, and people with MS, for many years.

"A number of theories have been suggested in the past, including the influence of hormones or possible genetic factors - and this study explores one such genetic factor in further detail, which is really interesting."

---


Pope Francis: end world hunger through 'Prayer and Action'


Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for June 2015
Universal:
That immigrants and refugees may find welcome and respect in the countries to which they come.
Evangelization: That the personal encounter with Jesus may arouse in many young people the desire to offer their own lives in priesthood or consecrated life.


Rosaries, Crosses, Prayer Cards and more... by Catholic Shopping .com


Comments


More Health

Lazy lifestyles pose dangerous and deadly threat to today's generation Watch

Image of Laziness can lead to problems with being overweight.

By Nikky Andres (NEWS CONSORTIUM)

You might not be entirely aware, but according to the World Health Organization, physical inactivity is now the fourth most notorious global killer. In fact, the impact of physical inactivity has been claimed as the reason for more fatalities than the collective effect ... continue reading


5 wonderful facts about sunscreen that you didn't know Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

The need to use sunscreen is something emphasized everyday, not only by dermatologists but also by the beauty industry, media, etc. It's basically everywhere. It is not an alien fact to us that using sunscreen religiously will help us combat premature aging, the risk ... continue reading


Is getting plastic surgery a sin against God? Watch

Image of Plastic surgery is considered a simple medical procedure nowadays but remains as an intriguing aspect for the Catholic Church.

By Linky C. (NEWS CONSORTIUM)

Plastic surgery may seem to be a common medical procedure for several individuals around the globe, but the Catholic Church still has different points of views when it comes to changing the naturally bestowed beauty from God. Some medical practitioners, on the other ... continue reading


'Swimming pool eyes' are not because of chlorine... but because of urine Watch

Image of Swimmers that use the pool for their toilet causes the urine to react with chlorine. This in turn creates a chemical compound that hurts the eyes.

By Catholic Online (NEWS CONSORTIUM)

In a sage bit of advice that has a double meaning - you may not want to "go" to a public swimming pool after you learn this disgusting fact. If you emerge from the pool with red, stinging, sensitive eyes, it is not because of the chlorine... it is because of ... continue reading


Recording reveals anesthesiologist's shocking verbal abuse against unconscious patient Watch

Image of An anesthesiologist [not pictured] is caught make rude comments about patient.

By Atarah Haely (NEWS CONSORTIUM)

Instead of simply recording his doctor's post-operation instructions, as intended, a Virginian man accidentally recorded the anesthesiologist's verbal onslaught against him while he was asleep. Concealing his identity, the patient filed a lawsuit, including the doctor ... continue reading


Eating 'Fitness Snacks' may not be the healthy alternative for staying fit Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

We often hear the term "fitness food" or see products that are marketed as a healthy and guilt-free alternatives to chocolates and chips, or a way to fight cravings and hunger pangs. But could these "fitness foods" really be the key to keeping oneself healthy and fit? ... continue reading


Have you been exposed to this common, 'cancer causing' chemical? Watch

Image of A chemical commonly used in herbicides may cause cancer in those exposed to it, though early evidence is not conclusive.

By Matt Waterson (NEWS CONSORTIUM)

A chemical in a common herbicide widely used in farm work may potentially pose a threat to humans who are exposed to it, a new report from a World Health Organization (WHO) research unit has found. LOS ANGELES, CA (Catholic Online) - The herbicide known as ... continue reading


Kim Jong-Un claims to create 'miracle drug' that cures AIDS, Ebola, SARS an MERS Watch

Image of Kim Jong Un claims to have found the cure for AIDS.

By Talia Ramos (NEWS CONSORTIUM)

While he's not working on his nuclear weapons project, North Korea's Kim Jong-Un reportedly has been busy creating a miracle drug. Curing and preventing diseases such as AIDS, Ebola, SARS and MERS, he claims to have succeeded in with his medical endeavor, despite years ... continue reading


Human breast milk sold online presents dangerous health risks to consumers Watch

Image of

By Talia Ramos (NEWS CONSORTIUM)

The growing craze of human breast milk sold online has concerned many health experts. According to them, there is no scientific evidence found stating that drinking human breast milk can help restore health, as believed by some fitness communities and those suffering ... continue reading


PATIENTS KILLED: Euthanizing without consent in Belgium Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

In Belgium, a law requires that euthanasia shall only be administered with clear and voluntary consent from patients. In 2002, Belgium passed the Euthanasia Act, which states that only voluntary euthanasia is legally acceptable. MUNTINLUPA, PHILIPPINES (Catholic ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Genesis 19:15-29
15 When dawn broke the angels urged Lot on, 'To your ... Read More

Psalm, Psalms 26:2-3, 9-10, 11-12
2 Probe me, Yahweh, examine me, Test my heart and my ... Read More

Gospel, Matthew 8:23-27
23 Then he got into the boat followed by his ... Read More

Saint of the Day

Saint of the Day for June 30th, 2015 Image

First Martyrs of the See of Rome
June 30: The holy men and women are also called the “Protomartyrs of ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter