Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

4/9/2014 (2 years ago)

Catholic Online (www.catholic.org)

Regenerated thymus in 'very old' mouse may lead to same in humans

A breakthrough which may pave the way for the technique to be used in humans has been uncovered by Scottish scientists. Researchers have been able to fully restore an organ in a living animal for the first time. 

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections.

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

4/9/2014 (2 years ago)

Published in Health

Keywords: Organ regeneration, mice, Scotland, Clare Blackburn


LOS ANGELES, CA (Catholic Online) - The team have successfully rebuilt the thymus of "very old" mice by reactivating a natural mechanism that gets shut down with age. The thymus is an organ found in front of the heart.

The rebuilt thymus was not only similar in structure and genetic detail to one in a young mouse -- but was also able to function again.

Check out our fine selection of Bibles -- by going here!

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections. It must be noted that the regenerated thymus was more than twice the size of the aged organs in the untreated mice.

"By targeting a single protein, we have been able to almost completely reverse age-related shrinking of the thymus," Clare Blackburn from Edinburgh's Medical Research Council (MRC) Center for Regenerative Medicine said. Blackburn also led the research.

"Our results suggest that targeting the same pathway in humans may improve thymus function and therefore boost immunity in elderly patients, or those with a suppressed immune system."

While the treated mice were making T-cells, Blackburn's research team could not yet establish whether the immune systems of the older mice were strengthened.

Before the technique can be tested in humans, Black burn says, researchers will need to conduct more animal experiments to make sure the regeneration process can be tightly controlled.
 
The thymus is the first organ to deteriorate as people age. This phenomenon causes the immune system to become less effective. As we grow older, we lose the ability to fight off new infections, such as flu.

Regenerative medicine is a fast-growing area of research and is chiefly focused on stem cells. One of the central aims is to harness the body's own repair mechanisms and manipulate them in a controlled way to treat disease.

Blackburn's team says that they targeted a part of the process by which the thymus degenerates, which is a protein called FOXN1 that helps control how key genes in the thymus are switched on.

The stem was then used genetically modified mice to enable them to increase levels of this protein using chemical signals.

Researchers managed to instruct immature cells in the thymus, which are similar to stem cells to rebuild the organ in the older mice.

---


'Help give every student and teacher Free resources for a world-class moral Catholic education'


Copyright 2017 - Distributed by THE CALIFORNIA NETWORK

Pope Francis Prayer Intentions for DECEMBER 2016
Universal:
End to Child-Soldiers: That the scandal of child-soldiers may be eliminated the world over.
Evangelization: Europe: That the peoples of Europe may rediscover the beauty, goodness, and truth of the Gospel which gives joy and hope to life.



Comments


More Health

The miraculous story of an atheist doctor who quit performing abortions after a visit from St. Thomas Aquinas Watch

Image of Dr. Stojan Adasevic has since become a major voice for the pro-life movement in Serbia.

By Marshall Connolly (CALIFORNIA NETWORK)

An abortionist abruptly quit performing abortions after he encountered St. Thomas Aquinas in a dream. He has since become an active pro-life voice, working to outweigh the crimes he once committed. LOS ANGELES, CA (California Network) -- In his dreams, he saw a field ... continue reading


Scientists scramble for PLAGUE VACCINE in face of possible BIOLOGICAL WARFARE Watch

Image of Scientists race to find vaccine for the plague.

By Kenya Sinclair (CALIFORNIA NETWORK)

The Medieval disease notorious for killing off one-third of Europe's entire population may be making a comeback - this time aimed straight for the United States. LOS ANGELES, CA (Catholic Online) - The bubonic plague, which originally spread through Europe at the hands ... continue reading


Why is this man suing a Catholic hospital for a hysterectomy? Watch

Image of Jionni Conforti is a woman, according to her DNA, but she believes she is a man. She is suing a Catholic hospital which refused to perform a hysterectomy for her.

By Marshall Connolly (CALIFORNIA NETWORK)

A woman who believes she is a man is suing a Catholic hospital because they have refused to perform an hysterectomy on her. According to a lawsuit, the hospital is obligated to perform the surgery. LOS ANGELES, CA (California Network) -- Jionni Conforti, 33, is a woman ... continue reading


Here are 10 great reasons why Planned Parenthood must be defunded Watch

Image of Republicans are about to exercise their right to choose and abort Planned Parenthood.

By David Drudge (CALIFORNIA NETWORK)

The Ethics and Religious Liberty Commission of the Southern Baptist Convention has published 10 reasons why taxpayers should defund Planned Parenthood. Thanks to the election of Donald Trump and a Republican-controlled House and Senate, this important goal is finally ... continue reading


Spicy discovery may change the future of cancer treatment forever Watch

Image of Scientists believe an ingredient in chili peppers can help cure cancer.

By Monique Crawford (CALIFORNIA NETWORK)

What do breasts, a rock band and science have in common? LOS ANGELES, CA (Catholic Online) - The Red Hot Chili Peppers are a popular rock band but those aren't the chili peppers scientists are excited about.Scientists from Ruhr University in Bochum, Germany discovered ... continue reading


Bill Gates is worried the world isn't ready for a pandemic outbreak of the flu -- What are your odds of dying in the next one? Watch

Image of The Spanish Flu killed between three and six percent of the world's population in just two years.

By Marshall Connolly (CALIFORNIA NETWORK)

Bill Gates is worried that the world is ill prepared to respond to a flu pandemic, should one occur. Doctors believe it is only a matter of time before the next major flu pandemic strikes. What are your odds of death? LOS ANGELES, CA (California Network) -- Bill Gates ... continue reading


IT'S A FACT - If you live a fat and lazy life, you will die younger than you should, so why are you still on the couch? Watch

Image of Couch potatoes are less likely to live long and fulfilling lives.

By David Drudge (CALIFORNIA NETWORK)

Most people in middle age are neglecting their health as they worry about other concerns. Nearly all people between the ages of 40 to 60 have poor lifestyle habits, and over two-thirds to three-quarters of men in this category are overweight. LOS ANGELES, CA ... continue reading


Government caught in MASSIVE COVERUP - Doctor claims '18 million people will die' Watch

Image of Why is the superbug death toll skewed?

By Kenya Sinclair (CALIFORNIA NETWORK)

The UK estimates at least 23,000 people die every year as a direct result of antibiotic-resistant superbugs - but are those number accurate? LOS ANGELES, CA (Catholic Online) - Dr. Ron Daniels, the chief executive of UK Sepsis Trust, believes the number of deaths by ... continue reading


Faith, science or a miracle? Doctors baffled at nun's high function despite aggressive Alzheimer's Watch

Image of One nun's brain revealed aggressive Alzheimer's yet she remained fully-functional and of sound mind.

By Monique Crawford (CALIFORNIA NETWORK)

Sister Bernadette was a famous participant of a Nun Study focused on understanding the horrors of Alzheimer's. What she contributed to the medical community changed everything previously believed about the debilitating disease. LOS ANGELES, CA (Catholic Online) - ... continue reading


Here's why all those c-sections are messing with evolution Watch

Image of Are c-sections driving evolution? All medical procedures that save lives are driving evolution to some extent.

By Marshall Connolly (CALIFORNIA NETWORK)

Repeated use of C-sections to give birth could be 'messing' with evolution, scientists say. As women with narrow pelvises survive childbirth, they are passing their genes to the next generation, increasing the population of women who cannot deliver children naturally. ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

Daily Readings

Reading 1, Hebrews 5:1-10
1 Every high priest is taken from among human beings and is appointed to ... Read More

Psalm, Psalms 110:1, 2, 3, 4
1 [Of David Psalm] Yahweh declared to my Lord, 'Take your seat at my ... Read More

Gospel, Mark 2:18-22
18 John's disciples and the Pharisees were keeping a fast, when some ... Read More

Saint of the Day

Saint of the Day for January 16th, 2017 Image

St. Fursey
January 16: Irish monastic founder, the brother of Sts. ... Read More