Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

4/9/2014 (11 months ago)

Catholic Online (www.catholic.org)

Regenerated thymus in 'very old' mouse may lead to same in humans

A breakthrough which may pave the way for the technique to be used in humans has been uncovered by Scottish scientists. Researchers have been able to fully restore an organ in a living animal for the first time. 

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections.

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

4/9/2014 (11 months ago)

Published in Health

Keywords: Organ regeneration, mice, Scotland, Clare Blackburn


LOS ANGELES, CA (Catholic Online) - The team have successfully rebuilt the thymus of "very old" mice by reactivating a natural mechanism that gets shut down with age. The thymus is an organ found in front of the heart.

The rebuilt thymus was not only similar in structure and genetic detail to one in a young mouse -- but was also able to function again.

Check out our fine selection of Bibles -- by going here!

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections. It must be noted that the regenerated thymus was more than twice the size of the aged organs in the untreated mice.

"By targeting a single protein, we have been able to almost completely reverse age-related shrinking of the thymus," Clare Blackburn from Edinburgh's Medical Research Council (MRC) Center for Regenerative Medicine said. Blackburn also led the research.

"Our results suggest that targeting the same pathway in humans may improve thymus function and therefore boost immunity in elderly patients, or those with a suppressed immune system."

While the treated mice were making T-cells, Blackburn's research team could not yet establish whether the immune systems of the older mice were strengthened.

Before the technique can be tested in humans, Black burn says, researchers will need to conduct more animal experiments to make sure the regeneration process can be tightly controlled.
 
The thymus is the first organ to deteriorate as people age. This phenomenon causes the immune system to become less effective. As we grow older, we lose the ability to fight off new infections, such as flu.

Regenerative medicine is a fast-growing area of research and is chiefly focused on stem cells. One of the central aims is to harness the body's own repair mechanisms and manipulate them in a controlled way to treat disease.

Blackburn's team says that they targeted a part of the process by which the thymus degenerates, which is a protein called FOXN1 that helps control how key genes in the thymus are switched on.

The stem was then used genetically modified mice to enable them to increase levels of this protein using chemical signals.

Researchers managed to instruct immature cells in the thymus, which are similar to stem cells to rebuild the organ in the older mice.

---


Pope Francis: end world hunger through 'Prayer and Action'


Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for March 2015
Universal:
Scientists: That those involved in scientific research may serve the well-being of the whole human person.
Evangelization: Contribution of women: That the unique contribution of women to the life of the Church may be recognized always.



Comments


More Health

Drink your coffee with confidence - daily java proven to prevent liver cancer Watch

Image of Coffee seems to protect people from liver cancer, which killed 746,000 people around the world in 2012.

By Catholic Online (NEWS CONSORTIUM)

There are many reasons to watch you alcoholic beverage intake. Researchers say more than three alcoholic drinks a day increases your risk for this highly deadly version of the disease. The good news: It appears that the consumption of coffee, rich in ... continue reading


New biomarker detects body reaction to chemotherapy improving cancer treatment Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

A reason many patients lose their chance of surviving ovarian cancer is because they are opting out of chemotherapy. With a recent discovery, researchers are hoping this new biomarker will help patients with high-grade serious ovarian cancer (HGSC) and thus, make ... continue reading


Are you washing your hair wrong? How to get hair salon results at home Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

Do you feel like you have bad hair almost everyday, but after you go to a salon, it feels like it has transformed into something completely different: silky and soft. Hairdressers have no magic tricks, but they have tips they've learned from training. You may actually ... continue reading


World's oldest evidence of breast cancer found in 4,200-year-old Egyptian skeleton Watch

Image of

By Catholic Online (NEWS CONSORTIUM)

While one of the leading causes of death, cancer is virtually absent in archaeological records of ancient man. The notion that modern lifestyles, people living longer and man-made chemicals being responsible for the disease has been accepted as a given by many. ... continue reading


5 Most Important Foods for Beautiful Healthy Hair Watch

Image of When it comes to healthy hair, it's not just what you put on your hair that counts it is your diet that matters most!

By Wendy RN., BA, MBA

Who doesn't want a gorgeous, glossy mane of beautiful, bouncy, shiny healthy hair. The secret is more about what we eat, than all the expensive products that we put on our hair.  LOS ANGELES, CA - (Rise Above Health), Regardless of the type of hair you have, the ... continue reading


Doctors say daily dose of cereal is good for you! Here's why Watch

Image of The findings, published in the journal BMC Medicine, suggest that the cereal fiber component of whole grains accounts for the actions of the whole grains, and that cereal fiber-rich whole grain foods may have health benefits.

By Catholic Online (NEWS CONSORTIUM)

Most people start their day with a bowl of cereal, porridge or oatmeal - and it is actually good for you! Doctors say that a diet high in grain cuts the risk for both cancer and diabetes. LOS ANGELES, CA (Catholic Online) - Starting the day this way can add years ... continue reading


Once-a-day tablet said to 'turn off cancer' Watch

Image of One of only a handful of new medicines to be made available via the Cancer Drugs Fund, two trials in 28 British hospitals found Ibrutinib to be extremely effective in treating both mantle cell lymphoma, or MCL and chronic lymphocytic leukemia, or CLL.

By Catholic Online (NEWS CONSORTIUM)

Ibrutinib, hailed as a revolutionary drug capable of "switching off" cancer may soon be offered to patients with some forms of the disease. The once-a-day tablet could spare blood cancer patients the sometimes-agonizing side effects of chemotherapy. LOS ... continue reading


Is your child on the wrong path? Childhood inactivity could lead to becoming 'middle-aged couch potatoes' Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

Inactive children are more likely to grow up and become middle-aged couch potatoes, as reported by BBC News. The findings, in a study from University College London, were children at age 10, who spent most of their time watching television shows are 42 percent more ... continue reading


Drinking diet soda may actually increase belly fat: New study dissects the link between artificial sweeteners and your waistline Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

New studies show consumption of diet soda leads to belly fat. The presence of belly fat may be what medical studies has been missing in the analysis between artificial sweeteners and serious health risks, although some other factors can contribute. MUNTINLUPA, ... continue reading


Why do mosquitoes find some people irresistible? The unbelievable reason lies in your skin Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

Twenty percent of all humans are more prone to being bitten by mosquitoes; 85 percent of the reason why is based on our genetic makeup, says Craig Benzine, the presenter in a video produced by Mental Floss. Sweating, body temperature, bathing and blood type all ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Jeremiah 20:10-13
10 I heard so many disparaging me, 'Terror on every ... Read More

Psalm, Psalms 18:2-3, 3-4, 5-6, 7
2 Yahweh is my rock and my fortress, my deliverer is ... Read More

Gospel, John 10:31-42
31 The Jews fetched stones to stone him,32 ... Read More

Saint of the Day

Saint of the Day for March 27th, 2015 Image

St. Rupert
March 27: Bishop and missionary, also listed as Robert of Hrodbert. A ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter