Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

4/9/2014 (1 year ago)

Catholic Online (www.catholic.org)

Regenerated thymus in 'very old' mouse may lead to same in humans

A breakthrough which may pave the way for the technique to be used in humans has been uncovered by Scottish scientists. Researchers have been able to fully restore an organ in a living animal for the first time. 

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections.

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

4/9/2014 (1 year ago)

Published in Health

Keywords: Organ regeneration, mice, Scotland, Clare Blackburn


LOS ANGELES, CA (Catholic Online) - The team have successfully rebuilt the thymus of "very old" mice by reactivating a natural mechanism that gets shut down with age. The thymus is an organ found in front of the heart.

The rebuilt thymus was not only similar in structure and genetic detail to one in a young mouse -- but was also able to function again.

Check out our fine selection of Bibles -- by going here!

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections. It must be noted that the regenerated thymus was more than twice the size of the aged organs in the untreated mice.

"By targeting a single protein, we have been able to almost completely reverse age-related shrinking of the thymus," Clare Blackburn from Edinburgh's Medical Research Council (MRC) Center for Regenerative Medicine said. Blackburn also led the research.

"Our results suggest that targeting the same pathway in humans may improve thymus function and therefore boost immunity in elderly patients, or those with a suppressed immune system."

While the treated mice were making T-cells, Blackburn's research team could not yet establish whether the immune systems of the older mice were strengthened.

Before the technique can be tested in humans, Black burn says, researchers will need to conduct more animal experiments to make sure the regeneration process can be tightly controlled.
 
The thymus is the first organ to deteriorate as people age. This phenomenon causes the immune system to become less effective. As we grow older, we lose the ability to fight off new infections, such as flu.

Regenerative medicine is a fast-growing area of research and is chiefly focused on stem cells. One of the central aims is to harness the body's own repair mechanisms and manipulate them in a controlled way to treat disease.

Blackburn's team says that they targeted a part of the process by which the thymus degenerates, which is a protein called FOXN1 that helps control how key genes in the thymus are switched on.

The stem was then used genetically modified mice to enable them to increase levels of this protein using chemical signals.

Researchers managed to instruct immature cells in the thymus, which are similar to stem cells to rebuild the organ in the older mice.

---


Pope Francis: end world hunger through 'Prayer and Action'


Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for May 2015
Universal:
That, rejecting the culture of indifference, we may care for our neighbours who suffer, especially the sick and the poor.
Evangelization: That Mary's intercession may help Christians in secularized cultures be ready to proclaim Jesus.


Rosaries, Crosses, Prayer Cards and more... by Catholic Shopping .com


Comments


More Health

Brain reset: Scientists uncover unusual way to get rid of brain disorders Watch

Image of

By Atarah Haely (NEWS CONSORTIUM)

By implanting special cells that emit GABA into the brains of adult mice scientists found a way to cure certain brain disorders, like lazy eye. Initially an almost impossible endeavor, the experiment led a team of scientists to a way to reset the brain and basically ... continue reading


Health in the United States: Which cities are the healthiest? Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

The American College of Sports Medicine has recently released their 2015 American Fitness Index, naming the top three fittest and the least fit cities in the entire United States. MUNTINLUPA, PHILIPPINES (Catholic Online) -  Among the thousands of cities surveyed ... continue reading


Nebraska orders STATE OF EMERGENCY over H5N2 avian flu virus Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

A type of avian flu, and unfortunately the most lethal to hit the United States, has posed several concerns for farmers and scientists. So far, the H5N2 strain of the bird flu virus has already killed 15,000 turkeys in Minnesota alone. Now, over 33 million birds in 16 ... continue reading


Why a handshake just might save your life Watch

Image of Handshakes may be able to determine your risk for heart disease or other illnesses.

By Matt Waterson (NEWS CONSORTIUM)

Are you worried about a heart attack or stroke? Well there may be an easy way to tell if you are at greater risk for either of these diseases, are near death or seriously ill, and you don't need anything more than a hand and a partner. LOS ANGELES, CA (Catholic ... continue reading


Are you afraid of needles? Scientist believes he found way to reduce injection pain Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

A lot of people, the young and old alike, are really frightened of getting injections, even just the thought of it. The good news is that scientists have discovered a simple answer. MUNTINLUPA, PHILIPPINES (Catholic Online) - Spanish scientists believe that holding ... continue reading


Woman gives shocking birth to baby born with bladder outside of body Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

Born with a rare congenital defect, Baby Lila underwent a unique surgery, shortly after she was born with her bladder outside the body. This defect was detected when the doctor couldn't find her bladder in a sonogram conducted during the 22-week prenatal appointment. ... continue reading


What do healthy people eat for breakfast? 11 healthy breakfast choices from dietitians and experts Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

What we eat in the mornings have an effect on our energy levels throughout the day. Here, registered dietitians, personal trainers, health editors and nutritionists, suggest healthy breakfasts for a healthy morning start, with some help from BuzzFeed. MUNTINLUPA, ... continue reading


NOT-SO HAPPY PILLS: Half a million patients die every year from psychiatric drugs Watch

Image of Professor Peter Gotzsche, research director at Denmark's Nordic Cochrane Center says the use of most antidepressants and dementia drugs could be discontinued without harm.

By Catholic Online (NEWS CONSORTIUM)

A Danish scientist has come forward to proclaim that mood enhancers, "happy pills" and other psychiatric drugs are frequently deadly - killing half a million people a year. Furthermore, he says that these medications are usually ineffective - not producing the ... continue reading


British man discovers shocking and disturbing item in phlegm he coughed out Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

A man from Britain woke up to a very unlikely and disgusting surprise. After waking up, the man felt as though he had to let out a cough due to the "large phlegm ball" he was feeling inside. To his surprise, he found something completely more nauseating than mucus. ... continue reading


Good Morning America's Robin Roberts speaks on her near death medical experiences Watch

Image of

By Talia Ramos (NEWS CONSORTIUM)

After bravely beating breast cancer, Good Morning America host Robin Roberts developed a myelodysplastic syndrome (MDS) that nearly claimed her life after a bone marrow transplant in 2012. She recalled her near death story and how she was saved by the pleas of a nurse ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Acts 2:1-11
1 When Pentecost day came round, they had all met ... Read More

Psalm, Psalms 104:1, 24, 29-30, 31, 34
1 Bless Yahweh, my soul, Yahweh, my God, how great ... Read More

Gospel, John 20:19-23
19 In the evening of that same day, the first day of ... Read More

Reading 2, First Corinthians 12:3-7, 12-13
3 Because of that, I want to make it quite clear to ... Read More

Saint of the Day

Saint of the Day for May 24th, 2015 Image

St. David I of Scotland
May 24: David, the youngest son of Scotlandís virtuous queen, (Saint) ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter