Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

4/9/2014 (2 years ago)

Catholic Online (www.catholic.org)

Regenerated thymus in 'very old' mouse may lead to same in humans

A breakthrough which may pave the way for the technique to be used in humans has been uncovered by Scottish scientists. Researchers have been able to fully restore an organ in a living animal for the first time. 

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections.

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

4/9/2014 (2 years ago)

Published in Health

Keywords: Organ regeneration, mice, Scotland, Clare Blackburn


LOS ANGELES, CA (Catholic Online) - The team have successfully rebuilt the thymus of "very old" mice by reactivating a natural mechanism that gets shut down with age. The thymus is an organ found in front of the heart.

The rebuilt thymus was not only similar in structure and genetic detail to one in a young mouse -- but was also able to function again.

Check out our fine selection of Bibles -- by going here!

After the regeneration, the treated mice also started to make more T-cells, which is a type of white blood cell key to fighting infections. It must be noted that the regenerated thymus was more than twice the size of the aged organs in the untreated mice.

"By targeting a single protein, we have been able to almost completely reverse age-related shrinking of the thymus," Clare Blackburn from Edinburgh's Medical Research Council (MRC) Center for Regenerative Medicine said. Blackburn also led the research.

"Our results suggest that targeting the same pathway in humans may improve thymus function and therefore boost immunity in elderly patients, or those with a suppressed immune system."

While the treated mice were making T-cells, Blackburn's research team could not yet establish whether the immune systems of the older mice were strengthened.

Before the technique can be tested in humans, Black burn says, researchers will need to conduct more animal experiments to make sure the regeneration process can be tightly controlled.
 
The thymus is the first organ to deteriorate as people age. This phenomenon causes the immune system to become less effective. As we grow older, we lose the ability to fight off new infections, such as flu.

Regenerative medicine is a fast-growing area of research and is chiefly focused on stem cells. One of the central aims is to harness the body's own repair mechanisms and manipulate them in a controlled way to treat disease.

Blackburn's team says that they targeted a part of the process by which the thymus degenerates, which is a protein called FOXN1 that helps control how key genes in the thymus are switched on.

The stem was then used genetically modified mice to enable them to increase levels of this protein using chemical signals.

Researchers managed to instruct immature cells in the thymus, which are similar to stem cells to rebuild the organ in the older mice.

---


Pope Francis: end world hunger through 'Prayer and Action'


Copyright 2016 - Distributed by THE CALIFORNIA NETWORK

Pope Francis Prayer Intentions for June 2016
Universal:
Human Solidarity: That the aged, marginalized, and those who have no one may find–even within the huge cities of the world–opportunities for encounter and solidarity.
Evangelization: Seminarians and Novices: That seminarians and men and women entering religious life may have mentors who live the joy of the Gospel and prepare them wisely for their mission.



Comments


More Health

Social anxiety a thing of the past? Scientists observe OXT Watch

Image of Are your social skills lacking? It may be in your genes (Shutterstock).

By Kenya Sinclair (CALIFORNIA NETWORK)

Have you always been more of a loner than social butterfly? Science may have proven why that is. LOS ANGELES, CA (Catholic Online) - Scientists may have found a reason why you're more comfortable alone than at a party.According to a study conducted by the University of ... continue reading


Top 7 healthy summer snacks Watch

Image of If you live in a region where the summer heat drains the energy out of you, these healthy summer treats are right up your alley (Gina's Recipes)!

By Kenya Sinclair (CALIFORNIA NETWORK)

Take a look at our top seven beautiful, delicious and healthy summer snacks! LOS ANGELES, CA (Catholic Online) - Images of sunny beaches, warm breezes, lake swims, ice cream and the laughter of children come to mind when we think of summer - but let's face it, we ALL ... continue reading


'We're sort of in a hard place': 234 pregnant women in U.S. diagnosed with Zika Watch

Image of Over 200 pregnant women in the U.S. have been diagnosed with the incurable Zika virus (Alamy).

By Kenya Sinclair (CALIFORNIA NETWORK)

No one is immune - over 200 pregnant women in the United States have been diagnosed with the Zika virus. LOS ANGELES, CA (Catholic Online) - A new CDC report revealed 234 pregnant women in the United States have been diagnosed with the Zika virus.Thus far, three babies ... continue reading


Can 'ethically acceptable' stem cell therapy cure MS? Watch

Image of Can stem cells cure MS (WikiMedia Commons)?

By (CNA/EWTN News)

A risky adult stem cell clinical trial in Canada has proven effective in stopping and even reversing the symptoms in patients with severe cases of multiple sclerosis, a progressive disease of the immune system that is often untreatable. Ontario, Canada (CNA/EWTN News) ... continue reading


Archbishop speaks out after California legalizes assisted suicide Watch

Image of Why offer end of life options if assisted suicide is the next best thing (thislittlecreekhealthcare)?

By (CNA/EWTN News)

Assisted suicide will change California for the worse, Archbishop Jose Gomez of Los Angeles said on Wednesday, adding that Catholics and others must take action to show they will care for the ailing, not aid in killing them. Los Angeles, CA (CNA/EWTN News) - "With the ... continue reading


SICK and SAD: England approves procedure that allows a baby to have 3 parents, but it kills dozens of others in the process Watch

Image of Doctors can now create a baby with donated mitochondria from a second mother.

By Marshall Connolly (CALIFORNIA NETWORK)

In England, it is now both possible and legal to have a child with three biological parents. The process is called "three person IVF." The practice is fraught with ethical concerns. LOS ANGELES, CA (California Network) - Three person in-vitro fertilization can allow ... continue reading


Should I kill myself or buy a t-shirt? Watch

Image of Between the tee shirt shops and the pot shops, is a place for people to obtain poison to end their lives.

By Marshall Connolly (CALIFORNIA NETWORK)

Should I kill myself or buy a t-shirt? This is the question some visitors to Berkeley might have as they visit the college town just east of Oakland. The reason is that California's "right to die" law goes into effect today and along with it, the first clinic ... continue reading


Does cellphone radiation REALLY cause cancer? Watch

Image of Research indicates cellular radiation causes cancer in rats - but does it do the same to humans (motion.pl/Shutterstock)?

By Kenya Sinclair (CALIFORNIA NETWORK)

A new study reveals startling information concerning cancers growing in rats exposed to cell phone radiation. How safe are you from similar cancers? LOS ANGELES, CA (Catholic Online) - The study, conducted by research and education institution bioRxiv, revealed ... continue reading


Woman diagnosed with 'nightmare bacteria' in US Watch

Image of A woman has been diagnosed with a frightening E. coli superbug in Pennsylvania (Inhabitat).

By Kenya Sinclair (CALIFORNIA NETWORK)

A 49-year-old Pennsylvanian woman who has not stepped foot outside the United States within the past several months was recently diagnosed with the first case of its kind in the US - a drug-resistant form of E. coli. LOS ANGELES, CA (Catholic Online) - The CDC and ... continue reading


HORRIFYING: Abortion mill calls 911 to save baby after botched abortion Watch

Image of A baby is a human being, even before it is born. There should be no question of its right to life.

By Marshall Connolly (CALIFORNIA NETWORK)

A chilling recording has been released on a 911 call from an abortion mill, requesting emergency services for a baby who survived an abortion. The call was placed earlier this year and left people wondering about the fate of the baby. It also raised the issue of the ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

the FEED
by Catholic Online

Daily Readings

Reading 1, Isaiah 49:1-6
1 Coasts and islands, listen to me, pay attention, distant peoples. ... Read More

Psalm, Psalms 139:1-3, 13-14, 14-15
1 [For the choirmaster Of David Psalm] Yahweh, you examine me and know ... Read More

Gospel, Luke 1:57-66, 80
57 The time came for Elizabeth to have her child, and she gave birth to a ... Read More

Reading 2, Acts 13:22-26
22 he deposed him and raised up David to be king, whom he attested in ... Read More

Saint of the Day

Saint of the Day for June 24th, 2016 Image

St. John the Baptist
June 24: John the Baptist was a contemporary of Christ who ... Read More