Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

9/12/2013 (2 years ago)

Catholic Online (www.catholic.org)

Nine out of 16 monkeys infected with SIV respond favorably to vaccine

A vaccine for the primate equivalent of HIV appears to eradicate the virus, a study suggests. Sixteen monkeys infected with Simian Immunodeficiency Virus, or SIV were given a vaccine. Nine of the 16 test subjects responded favorably. Scientists in the United States say they now want to use a similar approach to test a vaccine for HIV in humans.

Of the test subject monkeys that successfully responded to the vaccine, all were clear of infection between one-and-a-half to three years later.

Of the test subject monkeys that successfully responded to the vaccine, all were clear of infection between one-and-a-half to three years later.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

9/12/2013 (2 years ago)

Published in Health

Keywords: Nine out of 16 monkeys infected with SIV respond favorably to vaccine


LOS ANGELES, CA (Catholic Online) - "It's always tough to claim eradication - there could always be a cell which we didn't analyze that has the virus in it," Professor Louis Picker, from the Vaccine and Gene Therapy Institute at Oregon Health and Science University, says. 

"But for the most part, with very stringent criteria... there was no virus left in the body of these monkeys."

Picker and his colleagues looked at an aggressive form of virus called SIVmac239, up to 100 times more deadly than HIV. Monkeys with SIV usually die within two years. However - in some inoculated primates, the virus did not take hold.

The vaccine is based on another virus called cytomegalovirus, or CMV, which belongs to the herpes family. The infectious power of CMV sweeps through the body. Instead of causing disease, CMV has been modified to spur the immune system into action to fight off the SIV molecules.

"It maintains an armed force, that patrols all the tissues of the body, all the time, indefinitely," Picker explains.

In the study, researchers gave rhesus macaque monkeys the vaccine, and then exposed them to SIV. The infection at first began to establish and spread. In time, the monkeys' bodies began to respond, and sought out and destroying all signs of the virus.

Of the test subject monkeys that successfully responded to the vaccine, all were clear of infection between one-and-a-half to three years later.

A mystery remains: Picker said his team was still trying to work out why the vaccination worked in only about half of the monkeys. "It could be the fact that SIV is so pathogenic that this is the best you are ever going to get.

"There is a battle going on, and half the time the vaccine wins and half the time it doesn't," he said.

In regards to application to human beings, researchers are now testing the vaccine to see if it can be used after SIV exposure to treat and perhaps cure infected monkeys - as a step to testing it on humans.

"In order to make a human version we have to make sure it is absolutely safe," Picker says. We have now engineered a CMV virus which generates the same immune response but has been attenuated [modified to lose its virulence] to the point where we think it is unequivocally safe."

This would first have to pass through the regulatory authorities, but if it does, he said he hoped to start the first clinical trials in humans in the next two years.

Watch Catholic Online's most viral videos here!

 

---


Pope Francis: end world hunger through 'Prayer and Action'


Copyright 2015 - Distributed by THE CALIFORNIA NETWORK

Pope Francis Prayer Intentions for February 2016
Universal:
That prisoners, especially the young, may be able to rebuild lives of dignity.
Evangelization: That married people who are separated may find welcome and support in the Christian community.



Comments


More Health

Native American Health Facilities 'Horrifying' Practices: Woman dies on floor of hospital room after staff causes her to overdose Watch

Image of Native American health facilities (not pictured) are so underfunded that poorly trained staff are responsible for serious illnesses and even preventable deaths.

By Kenya Sinclair (CALIFORNIA NETWORK)

During a Senate hearing on Wednesday, several witnesses stepped forward to ask the federal government to fund the struggling Indian Health Service, only to be told that government officials were unable to procure the necessary resources. LOS ANGELES, CA (Catholic ... continue reading


Florida Gorvernor declares state of emergency with Zika virus outbreak Watch

Image of At least nine people have been diagnosed with the Zika Virus in Florida (James Gathany/CDC).

By Kenya Sinclair (CALIFORNIA NETWORK)

Florida Governor Rick Scott declared a state of emergency after nine cases were diagnosed from people who travelled to Zika-dense regions. LOS ANGELES, CA (Catholic Online) - The state of emergency affects Tampa Bay, south and southwest Florida and Santa Rosa County. ... continue reading


Zika virus sexually transmitted in first U.S. case Watch

Image of Zika has been transmitted within the United States.

By Kenya Sinclair (CALIFORNIA NETWORK)

The first known case of the Zika virus being locally acquired in the United States has occured in Dallas, Texas. LOS ANGELES, CA (Catholic Online) - Dallas County health officials confirmed a recent traveler to Venezuela infected their partner after a sexual ... continue reading


Has the origin of the dangerous Zika virus been found? What really started the outbreak? Watch

Image of Women returning from affected areas are being warned to postpone conceive for at least a month in case they have been infected (India News).

By Catholic Online (CALIFORNIA NETWORK)

Most of Latin America - along with the rest of the world, is frantically trying to come to grips with an outbreak of Zika. The mosquito-borne illness usually leaves patients with mild, flu-like symptoms but causes a wide variety of birth defects to expectant ... continue reading


Scientists get permission to carry out horrifying genetic experiments on babies, then destroy them! Watch

Image of The era of designer babies is about to begin. The only cost is the lives of hundreds, possibly thousands of other babies.

By Marshall Connolly, Catholic Online (CALIFORNIA NETWORK)

Scientists in England have been given permission to start genetic experiments with unborn children. The scientists intend to turn off genes in between 30 - 120 unborn children just to see what happens. They claim the experiments will give them new insights that can aid ... continue reading


Is Alzheimer's contagious? Find out NOW! Watch

Image of Doctors continue to investigate whether Alzheimer's can be spread from one person to another (Alamy).

By Kenya Sinclair (CALIFORNIA NETWORK)

Professor John Collinge, the head of neurodegenerative disease at University College London, believes Alzheimer's disease can by transmissible from one person to another during invasive medical procedures -but is he right? LOS ANGELES, CA (Catholic Online) - In a study ... continue reading


Zika virus may halt Olympics as WHO calls emergency meeting for explosive spread of the virus Watch

Image of The Zika virus continues to spread, leading to babies born with smaller-than-normal heads and brain damage (Reuters).

By Kenya Sinclair (CALIFORNIA NETWORK)

Zika virus spreads so quickly and leaves such devastating effects on babies that Rio's Olympics may be cancelled. Meanwhile, the World Health Organization (WHO) has called an emergency meeting following explosive outbreaks. LOS ANGELES, CA (Catholic Online) - According ... continue reading


EVERYTHING you need to know about the dangerous Zika virus Watch

Image of Mothers in Jamaica are being discouraged from becoming pregnant until the Zika crisis has passed (YouTube).

By Anastasia Moloney, Thomson Reuters Foundation

The number of countries and territories in the Americas reporting cases of the mosquito-borne Zika virus rose to 22 on Tuesday, more than double the number a month ago, according to the Pan American Health Organization (PAHO). BOGOTA (Thomson Reuters ... continue reading


It's a hospital not a restaurant! The insane reason why the ACLU is suing a Catholic hospital Watch

Image of Mercy Hospital in Redding, CA has been under fore for refusing to perform a sterilization procedure on a patient.

By Marshall Connolly, Catholic Online (THE CALIFORNIA NETWORK)

Catholic healthcare is back in the news following an ACLU suit against Mercy Hospital in Redding, CA, over whether or not a patient has the right to demand a tubal ligation be performed at the facility following a C-section. A Superior Court judge has already sided ... continue reading


BREAKTHROUGH: Hormone found to extend lifespan by 40 percent Watch

Image of Professor Dixit adds that FGF21 is produced in the liver as an endocrine hormone. Levels of the hormone increase when calories are restricted to allow fats to be burned when glucose levels are low.

By Catholic Online (CALIFORNIA NETWORK)

A recently discovered hormone may provide the key to life extension, as well as improving the immune function. The hormone, as produced by the thymus gland, extends lifespan by 40 percent. LOS ANGELES, CA (Catholic Online) - Some researchers at the Yale School of ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Subscribe to Catholic OnlineYouTube Channel

the FEED
by Catholic Online

Daily Readings

Reading 1, First Kings 8:1-7, 9-13
1 Solomon then summoned the elders of Israel to Jerusalem to bring the ... Read More

Psalm, Psalms 132:6-7, 8-10
6 Listen, we heard of it in Ephrathah, we found it at ... Read More

Gospel, Mark 6:53-56
53 Having made the crossing, they came to land at Gennesaret and moored ... Read More

Saint of the Day

Saint of the Day for February 8th, 2016 Image

St. Jerome Emiliani
February 8: Jerome Emiliani lay chained in the dark dirty ... Read More