Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

7/15/2013 (1 year ago)

Catholic Online (www.catholic.org)

Tiny Immunocore of England harnesses T-cells to battle tumors

Two international pharmaceutical giants have their eyes set on a tiny, unassuming British startup company called Immunocore. Housed in a nondescript, single-story business park in Oxfordshire, Immunocore has found a way to use the mighty T-cell to fight tumors, paving the way for a possible cure for cancer.

Dr. Bent Jakobsen began the study T-cells 20 years ago while working at the Medical Research Council's Laboratory of Molecular Biology in Cambridge.

Dr. Bent Jakobsen began the study T-cells 20 years ago while working at the Medical Research Council's Laboratory of Molecular Biology in Cambridge.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

7/15/2013 (1 year ago)

Published in Health

Keywords: Immunocre, T-cells, Bent Jakobsen, immunotherapy, cancer


LOS ANGELES, CA (Catholic Online) - Immunocore has signed contracts with two of the biggest players in the pharmaceuticals industry in the last three weeks. The agreements may soon lead to a huge influx of cash in order to fund research on cancer immunotherapy, using the body's own immune system to fight tumor cells.

It's possible that Immunocore is the only company in the world that has developed a way of harnessing the power of the immune system's natural-born killer cells. T-cells found in the blood cells of humans, designed over millions of years of evolution to seek out and kill invading pathogens.

Executives of the drugs industry, known for their caution in funding research believes that Immunocore may have found a detour in order for future cancer patients are able to fend off their disease with their own immune defenses.

The former academics who set up Immunocore have worked hard on realizing their dream of developing a totally new approach to cancer treatment - and it is beginning to look as if it will finally pay off. "Immunotherapy is radically different," Bent Jakobsen, the Danish-born chief scientific officer of Immunocore says. Jakobsen began the study T-cells 20 years ago while working at the Medical Research Council's Laboratory of Molecular Biology in Cambridge.

"It doesn't do away with the other cancer treatments by any means, but it adds something to the arsenal that has one unique feature - it may have the potency to actually cure cancer," Jakobsen says.

Jakobsen and his colleague's research has piqued the interest of both Genentech in California, owned by the Swiss giant Roche, and Britain's GlaxoSmithKline. Both companies have signed deals with Immunocore that could result in up to half a billion pounds being invested in new cancer treatments based on its unique T-cell therapy.

Cancer immunotherapy, or immuno-oncology as it is technically called, represents a sea change in terms of cancer treatment. Cancer in the past has been largely treated by "slicing," via surgery, "poisoning" via chemotherapy or "burning" via radiotherapy. All three methods are burdened with the inherent problem of how to spare healthy tissue from irreparable damage while ensuring that every cancer cell is killed, deactivated or removed.

The new approach, based on the immune system, a complex web of cells, tissues and organs that constantly strive to keep the body free of disease, which almost certainly includes keeping cancerous cells in check.

Scientists have known for years that the immune system plays a key role in cancer prevention. There is ample evidence of this, not least from patients who are immune-suppressed in some way - they are more likely than other patients to develop cancer.

Many organizations have tried to develop anti-cancer treatments based on antibodies, with limited success, Jakobsen said. Part of the problem is that antibodies are not really designed to recognize cells. Immunocore has built a therapy around the second arm of the immune system, known as cellular immunity, where T-cells seek out and destroy invading pathogens.

"There are a lot of companies working with antibodies but we are virtually the only company in the world that has managed to work with T-cells. It has taken 20 years and from that point we are unique," Jakobsen says.

---


Pope Francis: end world hunger through 'Prayer and Action'


Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for March 2015
Universal:
Scientists: That those involved in scientific research may serve the well-being of the whole human person.
Evangelization: Contribution of women: That the unique contribution of women to the life of the Church may be recognized always.


Rosaries, Crosses, Prayer Cards and more... by Catholic Shopping .com


Comments


More Health

Ancient remedy using natural ingredients appears to stop 'superbug' Watch

Image of Modern researchers are researching why the salve works so effectively.

By Catholic Online (NEWS CONSORTIUM)

Methicillin-resistant Staphylococcus aureus, or MRSA, a flesh infection usually transmitted over lengthy hospital stays, may have met its match in an ancient, medieval potion that uses only natural ingredients. The seemingly magical potion, which contains ... continue reading


Your health is 'written' on your face: Facial imaging exposes the dramatic pace of aging Watch

Image of The process is a part of the

By Hannah Raissa Marfil (NEWS CONSORTIUM)

According to a report by a Chinese research team, facial features are proven more reliable in determining how fast a person is aging and some related health issues than the usual blood tests. MUNTINLUPA, PHILIPPINES (Catholic Online) - A report, published in the March ... continue reading


5 Super Simple Ways to help Age Proof your Eyes and Vision Watch

Image of Protect your eyes as they are very precious.

By Wendy RN., BA, MBA

Everyone wants to have good eyesight well into their later years. Here are 5 super easy ways to help protect your eyes and your vision. LOS ANGELES, CA - (Rise Above Health) Your eyes are an important part of your health. To make sure your eyes are healthy and you ... continue reading


Drink your coffee with confidence - daily java proven to prevent liver cancer Watch

Image of Coffee seems to protect people from liver cancer, which killed 746,000 people around the world in 2012.

By Catholic Online (NEWS CONSORTIUM)

There are many reasons to watch you alcoholic beverage intake. Researchers say more than three alcoholic drinks a day increases your risk for this highly deadly version of the disease. The good news: It appears that the consumption of coffee, rich in ... continue reading


New biomarker detects body reaction to chemotherapy improving cancer treatment Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

A reason many patients lose their chance of surviving ovarian cancer is because they are opting out of chemotherapy. With a recent discovery, researchers are hoping this new biomarker will help patients with high-grade serious ovarian cancer (HGSC) and thus, make ... continue reading


Are you washing your hair wrong? How to get hair salon results at home Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

Do you feel like you have bad hair almost everyday, but after you go to a salon, it feels like it has transformed into something completely different: silky and soft. Hairdressers have no magic tricks, but they have tips they've learned from training. You may actually ... continue reading


World's oldest evidence of breast cancer found in 4,200-year-old Egyptian skeleton Watch

Image of

By Catholic Online (NEWS CONSORTIUM)

While one of the leading causes of death, cancer is virtually absent in archaeological records of ancient man. The notion that modern lifestyles, people living longer and man-made chemicals being responsible for the disease has been accepted as a given by many. ... continue reading


5 Most Important Foods for Beautiful Healthy Hair Watch

Image of When it comes to healthy hair, it's not just what you put on your hair that counts it is your diet that matters most!

By Wendy RN., BA, MBA

Who doesn't want a gorgeous, glossy mane of beautiful, bouncy, shiny healthy hair. The secret is more about what we eat, than all the expensive products that we put on our hair.  LOS ANGELES, CA - (Rise Above Health), Regardless of the type of hair you have, the ... continue reading


Doctors say daily dose of cereal is good for you! Here's why Watch

Image of The findings, published in the journal BMC Medicine, suggest that the cereal fiber component of whole grains accounts for the actions of the whole grains, and that cereal fiber-rich whole grain foods may have health benefits.

By Catholic Online (NEWS CONSORTIUM)

Most people start their day with a bowl of cereal, porridge or oatmeal - and it is actually good for you! Doctors say that a diet high in grain cuts the risk for both cancer and diabetes. LOS ANGELES, CA (Catholic Online) - Starting the day this way can add years ... continue reading


Once-a-day tablet said to 'turn off cancer' Watch

Image of One of only a handful of new medicines to be made available via the Cancer Drugs Fund, two trials in 28 British hospitals found Ibrutinib to be extremely effective in treating both mantle cell lymphoma, or MCL and chronic lymphocytic leukemia, or CLL.

By Catholic Online (NEWS CONSORTIUM)

Ibrutinib, hailed as a revolutionary drug capable of "switching off" cancer may soon be offered to patients with some forms of the disease. The once-a-day tablet could spare blood cancer patients the sometimes-agonizing side effects of chemotherapy. LOS ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Isaiah 50:4-9
4 Lord Yahweh has given me a disciple's tongue, for ... Read More

Psalm, Psalms 69:8-10, 21-22, 31, 33-34
8 I am estranged from my brothers, alienated from my ... Read More

Gospel, Matthew 26:14-25
14 Then one of the Twelve, the man called Judas ... Read More

Saint of the Day

Saint of the Day for April 1st, 2015 Image

St. Hugh of Grenoble
April 1: Benedictine bishop of Grenoble, France, patron of St. Bruno. He ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter