Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

2/17/2013 (2 years ago)

Catholic Online (www.catholic.org)

Rare, one-of-a-kind disease may be treated with DNA mapping

Thirty-eight-year-old Briton Mandy Sellars has a rare disease that has made her legs grow freakishly huge, weighing 238 pounds by themselves. Now doctors say they have developed a promising treatment for her after mapping her DNA.

Incredibly difficult for her to move around, Mandy Sellars is housebound during the week. She travels in a specially reinforced wheelchair.

Incredibly difficult for her to move around, Mandy Sellars is housebound during the week. She travels in a specially reinforced wheelchair.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

2/17/2013 (2 years ago)

Published in Health

Keywords: Rare disease, gigantism, DNA mapping, United Kingdom


LOS ANGELES, CA (Catholic Online) - Sellars has a condition that has caused her legs to grow out of control her entire life. She had her massive left leg amputated after it became infected with septicaemia. Incredibly, the stump started growing again and within three years measured a meter in circumference and weighed 42 pounds.

Her condition is unnamed, following genetic testing. Her case is the first case of its kind in the world.

Incredibly difficult for her to move around, she is housebound during the week. She travels in a specially reinforced wheelchair.

Doctors had hoped to fit her with a prosthetic leg but as her stump kept growing, new legs had to be made and to date she is still unable to walk.

"I find it incredibly frustrating," Sellars, from Huncoat in Lancashire says. "I have such a zest for life and I really want to get out there and live it."

Scientists at Cambridge University took an interest in Sellars' case, and over the past year, Dr. Robert Semple has mapped her DNA from blood and tissue samples.

Sellars previously thought she had a rare form of Proteus Syndrome, the condition that affected the Elephant Man. However, the analysis revealed she had a unique disorder.

"I'm the first person in the world with it and it hasn't even got a name yet," she told a TV chat show. "I keep suggesting Dr Semple call it Sellars Syndrome!"

Dr. Semple's team has come up with a medication aimed at replacing her unique mutated gene with a therapeutic gene. "I started taking it in September and the aim was to stop my limbs growing further. Actually they have started to shrink a little," Sellars said.

"I just kind of accepted my condition would get worse and keep growing but I am more optimistic following the discovery."

A size 12 on her top half, Sellars has had to deal with her one in seven billion conditions her entire life.

"There was clearly something dramatically different about me when I was born as my legs were so much bigger than my body. Doctors didn't know what it was and whisked me away - they didn't let my mother see me for two weeks. They didn't think I would survive."

Despite of all of her hardships, Sellars remains optimistic. "I really miss travelling and I hope one day to walk again," she said. "I'm stubborn enough to make it happen!"

---


Pope Francis: end world hunger through 'Prayer and Action'


Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for February 2015
General Intention:
That prisoners, especially the young, may be able to rebuild lives of dignity.
Missionary Intention: That married people who are separated may find welcome and support in the Christian community.



Comments


More Health

Shocking 'medical miracle' birth startles doctors and parents Watch

Image of (Cedars-Sinai Medical Center in Los Angeles)

By Abigail James (NEWS CONSORTIUM)

Now dubbed a "medical miracle," the birth of Silas Philips took doctors by surprise when he was born still inside his amniotic sac. Silas' birth miracle is extremely rare, only 1 in 80,000 births are similar to his. LOS ANGELES, CA (Catholic Online) - When his mother ... continue reading


New pill dramatically cuts risk for AIDS transmission in homosexual men Watch

Image of Some 545 HIV-negative gay men, who were sexually active and had recently had unprotected sex, were recruited to the study.

By Catholic Online (NEWS CONSORTIUM)

A daily pill, pre-exposure prophylaxis, or PrEP has been found to dramatically cut a person's risk of contracting HIV. Following a trial in the United Kingdom, advocates say the drug must be made available as soon as possible. LOS ANGELES, CA (Catholic Online) ... continue reading


AT RISK: Formula-fed babies at risk for ingesting ARSENIC Watch

Image of While arsenic in home tap water was a source of the naturally occurring chemical, poisonous in large doses, the formula itself was a contributing factor as well.

By Catholic Online (NEWS CONSORTIUM)

Breastfeeding has long been deemed the healthiest nursing option for newborns. A new study from Dartmouth College bears this out: According to researchers, arsenic levels were more than seven times higher in formula-fed babies than in breastfed ones. LOS ... continue reading


Unbelievable: Secret to success may lie in your sleeping habits Watch

Image of New studies show the most successful people receive little sleep at night.

By Abigail James (NEWS CONSORTIUM)

Traditional research advises people between 18-64 years old get seven to nine hours of sleep for a healthy lifestyle. New studies are showing that some of the most successful and smartest people in the world rarely even get half of that amount of sleep a night. LOS ... continue reading


Closing door and throwing away the key: HIV vaccine proves SUCCESSFUL in monkeys Watch

Image of Given the drug, the test monkeys were able to fend off high, repeated doses of the simian version of the disease.

By Catholic Online (NEWS CONSORTIUM)

Comparing it to locking up an intruder and throwing away the key, scientists now say they have created an anti-HIV drug so powerful that it could work as a vaccine. The test trials have proven to be highly successful in Macaque monkeys.  LOS ANGELES, CA ... continue reading


Women are at risk: Dementia affects more women than men, quickly becoming number one killer Watch

Image of

By Abigail James (NEWS CONSORTIUM)

500,000 women are affected by dementia. This is compared to the 350,000 men who are afflicted. Dementia is quickly surpassing breast cancer or heart disease; it is becoming the newest disease that favors women. LOS ANGELES, CA (Catholic Online) - Not only is dementia ... continue reading


Unable to feel pain, rare medical condition haunts man's life with horrifying injuries Watch

Image of Undergoing a series of tests throughout his lifetime, it was not until 2011 that Steve Pete was given the genetic tests confirmed he and his brother Chris had genetic mutations of the SCN9A gene.

By Catholic Online (NEWS CONSORTIUM)

Steve Pete's parents knew something was wrong with their child when he chewed part of his tongue off while he was a baby. Pete suffers from a rare condition known as congenital analgesia, where he is unable to feel pain. Unable to detect physical discomfort, ... continue reading


Don't throw away those glasses yet! Lasik eye surgery found imperfect, even dangerous Watch

Image of The results of bad eye laser surgery include the necessitating of several glasses for both near and far-sighted vision, dry eyes and blurring of light sources at night.

By Catholic Online (NEWS CONSORTIUM)

Lasik eye surgery, where vision defects are cured with lasers, has a high success rate. However, anyone who undergoes the procedure must carefully weigh the risks. Those for whom the procedure fails must wear several glasses afterwards and suffer ailments. The ... continue reading


SAVING THOUSANDS OF LIVES: Medicare to cover lung cancer screening Watch

Image of A report projected that paying for lung cancer screening would cost Medicare $9 billion over five years, or about $3 per month per beneficiary.

By Catholic Online (NEWS CONSORTIUM)

A move that many are hailing as one that will save tens of thousands of lives, Medicare said this week that it will pay for lung cancer screening for people at the highest risk. Lung cancer remains the top cancer death for men in the United States and ... continue reading


AN END TO THE SNIFFLES? Amazing 'enigma machine' gives clues to common cold's origins Watch

Image of Using a computer-based model to identify a code in the viral genome, scientists from the Universities of Leeds and York studied what causes rhinoviruses, the most common group of viruses as well as the cause of most colds.

By Catholic Online (NEWS CONSORTIUM)

Colds are a given during the winter months: Close quarters, bad air and cold weather all conspire to send the most hearty home with a bad case of the sniffles. With all the medical advances, the cold continues to be humanity's bad-time friend. However - a new ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Ezekiel 18:21-28
21 'If the wicked, however, renounces all the sins he ... Read More

Psalm, Psalms 130:1-2, 3-4, 5-6, 7-8
1 [Song of Ascents] From the depths I call to you, ... Read More

Gospel, Matthew 5:20-26
20 'For I tell you, if your uprightness does not ... Read More

Saint of the Day

Saint of the Day for February 27th, 2015 Image

St. Leander of Seville
February 27: St. Leander of Seville, Bishop (Feast - February 27th) Leander ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter