Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

1/4/2013 (2 years ago)

Catholic Online (www.catholic.org)

Japanese research offers new path to fight cancer, HIV

Scientists in Japan have created cells capable of killing cancer for the first time. The breakthrough was made by researchers who were able to create cancer-specific killer T cells. The development leads the way for the cells to be directly injected into cancer patients for therapy.

Japanese researchers led by Hiroshi Kawamoto then reprogrammed mature human killer T lymphocytes into iPS cells and then investigated how these cells differentiate.

Japanese researchers led by Hiroshi Kawamoto then reprogrammed mature human killer T lymphocytes into iPS cells and then investigated how these cells differentiate.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

1/4/2013 (2 years ago)

Published in Health


LOS ANGELES, CA (Catholic Online) - While these cells naturally occur in small numbers, it's hoped injecting large quantities back into a patient could turbo-charge the immune system.

Researchers at the RIKEN Research Centre for Allergy and Immunology have announced their success in creating cancer-specific, immune system cells called killer T lymphocytes. Researchers reprogrammed T lymphocytes specialized in killing a certain type of cancer, into another type of cell called induced pluripotent stem cells, or iPS cells.

These iPS cells then generated the cancer-specific T lymphocytes. These lymphocytes regenerated from iPS cells could potentially serve as cancer therapy in the future.

Killer T lymphocytes in previous studies produced in lab conditions using conventional methods proved to be inefficient in killing cancer cells, due to their very short life-span, which limits their use as treatment for cancer.

Japanese researchers led by Hiroshi Kawamoto then reprogrammed mature human killer T lymphocytes into iPS cells and then investigated how these cells differentiate.

The team induced killer T lymphocytes specific for a certain type of skin cancer to reprogram into iPS cells by exposing the lymphocytes to the "Yamanaka factors," a group of compounds that induce cells to revert back to a non-specialized, stage.

The iPS cells obtained were then grown in the lab and induced to differentiate into killer T lymphocytes again. This new batch of T lymphocytes was shown to be specific for the same type of skin cancer as the original lymphocytes.

They maintained the genetic reorganization, enabling them to express the cancer-specific receptor on their surface. The new T lymphocytes were also shown to be active and to produce an anti-tumor compound.

"We have succeeded in the expansion of antigen-specific T cells by making iPS cells and differentiating them back into functional T cells," Kawamoto says.

"The next step will be to test whether these T cells can selectively kill tumor cells but not other cells in the body. If they do, these cells might be directly injected into patients for therapy. This could be realized in the not-so-distant future."

Dr Dusko Ilic, Senior Lecturer in Stem Cell Science, King's College London, is optimistic of this new branch of research. "The study tackled a novel, quite interesting approach to cell based therapy, something that we do not usually hear about," Ilic says.

"Although this approach requires further verification and a lot of work needs to be done before we can think about clinical trials, the initial data are promising.

"This pioneering work definitely provides a strong foundation to build and expand our knowledge about new opportunities in cell based therapy and personalized medicine."

---


Pope Francis: end world hunger through 'Prayer and Action'


Copywriter 2015 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for May 2015
Universal:
That, rejecting the culture of indifference, we may care for our neighbours who suffer, especially the sick and the poor.
Evangelization: That Mary's intercession may help Christians in secularized cultures be ready to proclaim Jesus.


Rosaries, Crosses, Prayer Cards and more... by Catholic Shopping .com


Comments


More Health

Is this the definitive cure for Ebola? Researchers find Ebola's 'Achilles heel' Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

Hope for new treatments that finally avert Ebola grows with the recent discovery from researchers that there is a weak spot within the deadly virus. According to researchers in New York, a specific protein that determines whether or not the Ebola virus can further ... continue reading


Milwaukee man shocks distraught family by 'coming back to life' Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

When a man from Milwaukee was pronounced dead last week, everyone, from his girlfriend to his brother, was immediately notified. The first responders made all the necessary arrangements for the corpse to be transported to the morgue. While all the preparations were ... continue reading


Revolutionary! Robotic arm controlled by thought provides breakthrough for paralyzed Watch

Image of

By Catholic Online (NEWS CONSORTIUM)

An exciting new breakthrough in robotics may now enable the paralyzed to command helpmates with everyday activity. The breakthrough came in form of 34-year-old Erik Sorto, paralyzed from the neck down after being shot in the back 13 years ago. Thanks to a ... continue reading


Ancient Chinese plant 'thunder god vine' studied as miracle drug for obesity Watch

Image of In developed nations, where food is inexpensive and plentiful, obesity has been an ongoing problem. Obesity causes heart disease, diabetes and increases the risk for heart attack and stroke.

By Catholic Online (NEWS CONSORTIUM)

A traditional Chinese medicine known as "thunder god vine" is being heralded by some scientists as the new miracle drug in the war against obesity. Scientists in an article published in the medical journal Cell last week said an extract made from the plant ... continue reading


Brain reset: Scientists uncover unusual way to get rid of brain disorders Watch

Image of

By Atarah Haely (NEWS CONSORTIUM)

By implanting special cells that emit GABA into the brains of adult mice scientists found a way to cure certain brain disorders, like lazy eye. Initially an almost impossible endeavor, the experiment led a team of scientists to a way to reset the brain and basically ... continue reading


Health in the United States: Which cities are the healthiest? Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

The American College of Sports Medicine has recently released their 2015 American Fitness Index, naming the top three fittest and the least fit cities in the entire United States. MUNTINLUPA, PHILIPPINES (Catholic Online) -  Among the thousands of cities surveyed ... continue reading


Nebraska orders STATE OF EMERGENCY over H5N2 avian flu virus Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

A type of avian flu, and unfortunately the most lethal to hit the United States, has posed several concerns for farmers and scientists. So far, the H5N2 strain of the bird flu virus has already killed 15,000 turkeys in Minnesota alone. Now, over 33 million birds in 16 ... continue reading


Why a handshake just might save your life Watch

Image of Handshakes may be able to determine your risk for heart disease or other illnesses.

By Matt Waterson (NEWS CONSORTIUM)

Are you worried about a heart attack or stroke? Well there may be an easy way to tell if you are at greater risk for either of these diseases, are near death or seriously ill, and you don't need anything more than a hand and a partner. LOS ANGELES, CA (Catholic ... continue reading


Are you afraid of needles? Scientist believes he found way to reduce injection pain Watch

Image of

By Nikky Andres (NEWS CONSORTIUM)

A lot of people, the young and old alike, are really frightened of getting injections, even just the thought of it. The good news is that scientists have discovered a simple answer. MUNTINLUPA, PHILIPPINES (Catholic Online) - Spanish scientists believe that holding ... continue reading


Woman gives shocking birth to baby born with bladder outside of body Watch

Image of

By Hannah Raissa Marfil (NEWS CONSORTIUM)

Born with a rare congenital defect, Baby Lila underwent a unique surgery, shortly after she was born with her bladder outside the body. This defect was detected when the doctor couldn't find her bladder in a sonogram conducted during the 22-week prenatal appointment. ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Sirach 42:15-25
15 Next, I shall remind you of the works of the Lord, ... Read More

Psalm, Psalms 33:2-3, 4-5, 6-7, 8-9
2 Give thanks to Yahweh on the lyre, play for him on ... Read More

Gospel, Mark 10:46-52
46 They reached Jericho; and as he left Jericho with ... Read More

Saint of the Day

Saint of the Day for May 28th, 2015 Image

Bl. Margaret Pole
May 28: Martyr of England. She was born Margaret Plantagenet, the niece ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter