Hong Kong researchers successfully perfect anti-aging process on mice
It is hoped that the process will have practical applications on human beings
A tragic condition that causes children to develop the signs of old age before their time, resulting in wrinkles and organ failure - called progeria, has led researchers in Hong Kong to successfully find the paths to halt the process in mice. It is hoped that this application will be shortly transferred to human beings.
Children afflicted with progeria become highly evident before the child turns a year old. Although their mental faculties are normal, the said afflicted children stop growing, lose body fat and suffer from wrinkled skin and hair loss.
Children afflicted with progeria become highly evident before the child turns a year old. Although their mental faculties are normal, the said afflicted children stop growing, lose body fat and suffer from wrinkled skin and hair loss. As is the case with the elderly, they suffer stiff joints and a buildup of plaque in arteries which can lead to heart disease and stroke. Most afflicted with the condition die before they are 20 years old.
The team at the University of Hong Kong found that a mutation in the Lamin A protein, which lines the nucleus in human cells, disrupted the repair process in cells, thus resulting in accelerated aging.
In their most recent work, which used both mice and experiments in petri dishes, they found that normal and healthy Lamin A binds to and activates the gene SIRT1, which experts have long associated with longevity.
"We can develop drugs that mimic Lamin A or increase the binding between Lamin A and SIRT1," Liu Baohua, research assistant professor of biochemistry at the University of Hong Kong said.
The team went then went to see if the binding efficiency between Lamin A and SIRTI would be boosted with resveratrol, a compound found in the skin of red grapes and other fruits. The compound has been heralded by some scientists and companies as a way to slow aging or remain healthy as people get older.
Study leader Associate professor Zhou Zhongjun said healthy mice fed with concentrated resveratrol fared significantly better than healthy mice not given the compound.
"We actually delayed the onset of ageing and extended the healthy lifespan," Zhou said of the mice.
Furthermore, mice with progeria lived 30 percent longer when fed with resveratrol compared with progerial mice not given the compound.
When asked if drinking red wine delays ageing and reduces the risk of heart disease, Zhou said the alcohol content in wine would cause harm before any benefit could be derived.
"The amount of resveratrol in red wine is very low and it may not be beneficial. But the alcohol will cause damage to the body," Zhou said.
Pope Francis Prayer Intentions for December 2013
General Intention: Victimized Children. That children who are victims of abandonment or violence may find the love and protection they need.
Missionary Intention: Prepare the Savior's Coming. That Christians, enlightened by the Word incarnate, may prepare humanity for the Savior's coming.
Rate This Article
Leave a Comment
More Health News
- FDA gives guidelines to limit use of antibiotics in livestock
- Exercise reduces chances of dementia, lengthy study concludes
- Obamacare crashing in model states like California as 70 percent of doctors opt out
- New hepatitis-C drug approved by FDA
- Donors from around the world say that an AIDS-free generation may be within sight
- Washington signing up more people for Medicaid than private plans
- Man documents ravages of diabetes to his feet as they decay within 10 DAYS
- Dementia epidemic only growing worse: 135 million sufferers could arrive by 2050
- Men are from Mars, Women from Venus? Their brains are certainly wired differently
- Fr. Paul Schenck: Finding Living Faith on Catechetical Sunday
- The Movie Yellow: Incest as 'Normal' and Cassavates's Slides Into the World of Woes
- The Chicago School Teachers Strike Reveals the Need For School Choice
- The Sexual Barbarians and the Dissolution of Culture
- The Happy Priest Challenges Us to Ask: Who is Jesus to Me?
- Michael Coren on Canadian Public Schools: Teachers, leave those kids alone
- We Cannot Ignore Our Consciences: Cardinal Dolan On Religious Liberty
- In the Face of Danger, Successor of Peter Travels to Lebanon as a Messenger of Peace
- Reflections on the Dignity and Vocation of Women: Who or What?