LOS ANGELES, CA (Catholic Online) - Scientists working with mice have focused their attention on a type of cell known as senescent cells. Senescent cells promote the aging of tissues, and have been connected with all the normal signs of aging such as loss of fat under the skin, the buildup of plaque within arteries of elderly patients, and the development of cataracts in the eye. The cells also contribute to the waste of muscle tissue and  low-level inflammation throughout the body.

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Scientists have now found a way to eliminate these cells.

Researchers tested on genetically modified mice that had their senescent cells marked so that when given a drug, the cells would self-destruct. Those mice that were given the drug to destroy the cells did not show the typical signs of aging that other mice displayed.

Specifically, the mice did not develop cataracts, their muscle tissue did not waste, and they were able to exercise much longer on treadmills. They did not lose the layers of fat under their skin which typically happens in humans and causes wrinkling.

The tests show that eliminating the cells can have a beneficial effect on mice. The mice used in this study did not have their lifespans increased, but that was because they were of a special strain of fast-aging mice that typically die young and are commonly used in experiments. 

A new round of tests on mice that age normally is currently being planned. Generally, laboratory mice can live up to three years. If those mice can be genetically modified so that there senescent cells can be destroyed with drugs, and their lifespans are increased, then researchers will have finally found a modern version of the fountain of youth.

At least for mice.

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